Emily Halnon

Emily Halnon is the Communications Associate at GHTC. Below is her reaction to a photo reception documenting programs in Kenya that GHTC hosted last week. As someone new to the field of global health, I am constantly gaining an appreciation for just how much progress has been made in very recent years, how fragile that progress is, and how critical it is to sustain support for the research efforts that will build upon this momentum. I’ve quickly learned that rhetoric does not exist in this field; when my colleagues, our incredible member organizations, or other leaders in global health stress that the world is on the brink of incredible breakthroughs that will save millions of lives around the world, it is because it is true. The photo reception hosted by the Global Health Technologies Coalition (GHTC) last week offered a visual reaffirmation of this fact, while the experiences of the speakers confirmed how impactful the last few years of research have been and how critical current research efforts are to lives across the globe. The photos were all taken during GHTC’s recent trip to Kenya to observe and document research projects supported by member organizations like the International Partnership for Microbicides (IPM), the International AIDS Vaccine Initiative (IAVI), Aeras, PATH, and the Drugs for Neglected Diseases initiative (DNDi) and US government agencies like the US Agency for International Development (USAID), the Department of Defense (DoD), and the Centers for Disease Control and Prevention (CDC). Speakers at the event included Dr. Ariel Pablos-Méndez, assistant administrator for USAID's Global Health Bureau, Dr. Robert Breiman, country director for CDC-Kenya, and Dr. Kayla Laserson, director of the Kenya Medical Research Institute/CDC Field Research Station. Speakers at the event included Dr. Ariel Pablos-Méndez, assistant administrator for USAID’s Global Health Bureau, Dr. Robert Breiman, country director for CDC-Kenya, and Dr. Kayla Laserson, director of the Kenya Medical Research Institute/CDC Field Research Station The display of photos at the event was physically split into two stories. Event attendees entered the room and saw the first story laid out in a semi-circle, showing the families and communities who have benefited from a longstanding US commitment to research and recent successes−polio vaccines that have reduced rates of the disease by more than 99 percent, technologies to detect emerging epidemics, and antiretrovirals that are giving new hope to people battling HIV. The second story lay on the other half of the room, forming another semi-circle, and focused on the ongoing research that has the potential to produce more lifesaving tools−a tuberculosis vaccine, progress toward an AIDS vaccine, and critical drugs to treat neglected tropical diseases. The reception centered around two stories. One showed how lifesaving tools are making a difference in communities across Kenya. The second showed how current research is on the cusp of developing some of the most exciting new tools in global public health in recent years. Dr. Laserson spoke about the significance of this physical layout, highlighting the impact of the “moving circle” of research breakthroughs. As someone, unlike me, who has been immersed in global health for years, Dr. Laserson has seen firsthand what a difference the tools shown through the first story have made in communities in both Kenya and around the world. As she pointed to the first half of the room, she talked about how it was within very recent memory that tools represented in the photos there, like insecticide-treated bednets to protect people from malaria, were in the research pipeline, with vital trials being conducted to test their efficacy. Now, bednets are standard across the world, protecting millions of children from the disease. Tools like insecticide-treated bednets to protect people from malaria, were in the research pipeline within recent memory. Now, bednets are standard across the world, protecting millions of children from the disease. Photo: Evelyn Hockstein/PATH The two other speakers, Dr. Pablos-Méndez and Dr. Breiman, reinforced the significance of recent years and the investments that have helped make tools that were once unimaginable a reality. Dr. Breiman reflected on the CDC’s partnership with the Kenyan government and how vital capacity building has been to fueling these research efforts. Dr. Pablos-Méndez discussed how important it is that USAID continue to prioritize the science and technology that is enabling the world to tackle long-standing health and development challenges. These efforts include USAID’s support for the work of GHTC members IAVI and the TB Alliance. Through listening to both speakers, it was clear they believe it is critical to continue supporting cutting edge efforts, inter-agency cooperation, and investments in science and technology that will continue to save the lives of people like those shown so captivatingly through the photos. As Dr. Laserson transitioned from lauding the success of current tools to treat malaria, she gestured around the circle to the other half of the room and stressed how incredible it is that we are now looking at a malaria vaccine to prevent the disease. The same is true for a number of health tools and diseases, she said. Thanks to the President’s Emergency Plan for AIDS Relief (PEPFAR) and the investments of the US Government, HIV treatment is now the norm. And the world is on the cusp of breakthroughs for new prevention and treatment options, such as using HIV treatment as prevention among discordant couples, a method that research has shown can reduce the risk of HIV transmission by 96 percent. If donors like the US government can sustain their commitment to research on HIV and AIDS and other global health diseases, then we can bring these lifesaving tools to the half of the room, where they will be introduced into communities and can become game changers that will save lives and bring the world one step closer to eliminating these diseases.

In countries like Kenya, some of the most incredible global health research is taking place to develop new drugs, vaccines, diagnostics and other health products. In addition, previous research has lead to the roll-out of lifesaving health tools such as HIV and AIDS drugs, vaccines to protect children from pneumonia, and insecticide-treated bednets to prevent malaria. Last week, the GHTC hosted a photo reception that represented the people, both Kenyan and American, who are making new lifesaving health tools a reality, as well as the families benefitting from ongoing research and past research successes. The reception centered around two stories. One showed how lifesaving tools are making a difference in communities across Kenya. The second showed how current research is on the cusp of developing some of the most exciting new tools in global public health in recent years. Lifesaving tools are making a difference A historical commitment to research from the US government has led to the development of innovative health tools that are saving lives around the world. People worldwide have benefited from the development of critical medicines like antiretrovirals to treat HIV and AIDS and drugs to treat childhood killers like diarrhea, vaccines to protect infants from pneumonia and polio, and insecticide-treated bednets to prevent malaria. In Kenya, many individuals and families credit these valuable health tools with saving their lives and ensuring their children can have healthy and long futures. Researchers at agencies like the Centers for Disease Control and Prevention, the Department of Defense, and the US Agency for International Development are making a difference on the ground in Kenya by leading the development and delivery of drugs, vaccines, diagnostics, and other health products. With sustained support from the United States, countries like Kenya will continue to see the impact of these lifesaving health tools that are helping people abroad and right here at home. Kisumu, Kenya: Calvin Lang'at, a nurse at Vihiga District Hospital, gives an infant an oral polio vaccine. Immunization campaigns have reduced polio rates by more than 99 percent worldwide, and the disease is now near eradication. Photo credit: PATH/Evelyn Hockstein Kibera, Kenya: The Centers for Disease Control and Prevention use technologies to control the spread of infectious disease and to act as a warning system for the emergence of possible epidemics. Handheld PDAs—like the one health worker Joseph Thomas is using above—help officials conduct disease surveillance among 28,500 residents in Kibera. Disease surveillance can also help drive research for new health products, by alerting officials to large disease burdens and the need for new prevention and treatment options. Photo credit: PATH/Evelyn Hockstein Kombewa, Kenya: Martha Omondi puts her daughter Mercy Gloria, who is three years old, under a mosquito net to take a nap. Insecticide-treated nets have prevented millions of children from contracting malaria in Africa. Photo credit: PATH/Evelyn Hockstein Siaya, Kenya: Faith Oduor holds her daughter Brittany’s hand while she receives treatment for malaria at the Siaya District Hospital in western Kenya. Malaria treatments, including pediatric artemisinin therapies such as Coartem, help to save the lives of children like Brittany across Africa. Photo credit: PATH/Evelyn Hockstein Elwesero, Kenya: Peter Lumumba, a father of six, was first diagnosed with HIV in 1987 and started antiretroviral treatment in 2006 through the Aids, Population, and Health Integrated Assistance (APHIA II) program. He said of his treatment, “I am now well. People are totally astonished … when we are telling people we are (HIV) positive, they will say, ‘No, you are lying.’ Without the research that led to this lifesaving medicine, I would have already died.” Photo credit: PATH/Evelyn Hockstein Elwesero, Kenya: Peter Lumumba, pictured above with his son, was first diagnosed with HIV in 1987 and started antiretroviral treatment in 2006. Peter is open with his family about the fact that he is HIV-positive and is taking antiretroviral drugs. In the year 2000, Kenya had just a handful of HIV-positive people taking antiretroviral drugs. Today, the country has a half-million people on these drugs, which have saved many from an early death. Photo credit: PATH/Evelyn Hockstein Vihiga, Kenya: Rister Kageha holds her daughter Sylvia Mboga, who is 14 months old, at the Vihiga District Hospital. Rister learned she was HIV-positive and was put on antiretrovirals one month before she gave birth to her daughter. Sylvia was given the antiretroviral nevirapine after birth and is HIV negative. Rister accessed drugs through the Aids, Population, and Health Integrated Assistance (APHIA II) program, which provides comprehensive health care and prevention services. APHIA II is supported by the US Agency for International Development and run by GHTC member PATH. Photo credit: PATH/Evelyn Hockstein On the cusp of new global health tools The world is on the cusp of some of the most exciting new global health tools in recent years, thanks in large part to groundbreaking research supported by the US government through agencies such as the Centers for Disease Control and Prevention, the Department of Defense, and the US Agency for International Development. Clinical trials are showing promising results for the first-ever malaria vaccine, as well as a host of new interventions to prevent HIV infections. Researchers are on the verge of developing new drugs to treat neglected diseases that affect the poorest of the poor. This incredible health research is producing breakthroughs that could save countless lives, and Kenya is among the countries at the forefront of these efforts. Several global health research projects in Kenya are on the verge of producing new lifesaving health tools, and the US government continues to be a key player in supporting these groundbreaking research efforts. In Kenya, researchers confirmed how critical continued support from the US will be in reaching the finish line to defeat malaria, tuberculosis, HIV and AIDS, pneumonia, and other neglected diseases. It is imperative that the United States continues to drive the momentum around these new tools, from discovery to delivery, so that this research can produce the results that will help communities across the globe. Siaya, Kenya: At the Kaminogeldo Primary School, two miles from Lake Victoria in western Kenya, a mother enrolls her child in a study that will provide new information about co-infection of malaria and schistosomiasis, which is a major problem in the area. Fishermen and children often contract schistosomiasis from snails that live in and around the lake. The study is being run by the Kenya Medical Research Institute/Centers for Disease Control and Prevention partnership. Photo credit: PATH/Evelyn Hockstein Nairobi, Kenya: Lucas Agura, a medical laboratory technologist who works with the Kenya Medical Research Institute on neglected tropical diseases, conducts research at the KEMRI headquarters laboratory. KEMRI works with GHTC member the Drugs for Neglected Diseases initiative on its efforts to create new treatments for visceral leishmaniasis, a painful and deadly disease that affects half a million people worldwide each year. Photo credit: PATH/Evelyn Hockstein Kisian, Kenya: Mosquito DNA samples are prepared for testing at the Kenya Medical Research Institute (KEMRI)/Centers for Disease Control and Prevention (CDC) Field Research Station. KEMRI and the CDC have been partnering together for more than 30 years in Kenya. Dr. Pauline Mwinzi, a principal research officer who works with KEMRI/CDC said, “Without the US funding…we wouldn’t be able to move the sophisticated research that we do now.” Photo credit: PATH/Evelyn Hockstein Siaya, Kenya: Mothers sign consent forms to enroll their children in a study to examine co-infection with malaria and schistosomiasis in the region, run by the Kenya Medical Research Institute/Centers for Disease Control and Prevention partnership. Local residents said they appreciated the study. "One in five children in this area do not survive to their fifth birthday," said Jack Oloo Otieno, the school board chair. "We don't really know the full extent of the problem of schistosomiasis. If all our kids have it—and that's what we suspect—it is doing such harm to them. So we want as much information as possible, and this study will help." Photo credit: PATH/Evelyn Hockstein Kisian, Kenya: Wilfred Murithi, assistant research officer at the Kenya Medical Research Institute/Centers for Disease Control and Prevention facility in Kisian, prepares a sample to detect tuberculosis (TB) resistance to ritampicin, a TB drug. Resistance to TB drugs has become a severe problem in parts of the world and is increasing. There are an estimated 440,000 cases of multi-drug resistant TB globally, and at least 58 countries have reported cases of extensively drug resistant TB, which can be incurable. New TB drugs are desperately needed. Photo credit: PATH/Evelyn Hockstein Rawa, Kenya: Sharon Akinyi Ouma holds her daughter Winfrey Juma, who is 16 months old, outside their rural home in western Kenya. Sharon said she was happy to join a tuberculosis vaccine trial run by GHTC member Aeras in collaboration with the Kenya Medical Research Institute/Centers for Disease Control and Prevention. “I think of so many babies, so many children in Africa and around the world, have been helped by vaccines,” she said. “If this vaccine works, that means all those children will be helped by my baby’s participation. That makes me feel very good.” Photo credit: PATH/Evelyn Hockstein Nairobi, Kenya: Robert Langat, a lab technologist at the Kenya AIDS Vaccine Initiative (KAVI) in Nairobi, checks on vaccine samples stored in deep freeze at the laboratory. The US Agency for International Development supports a partnership KAVI maintains with GHTC member the International AIDS Vaccine Initiative to identify prevention strategies and a response to HIV and AIDS. In 1999, the partnership helped discover broadly neutralizing HIV antibodies—a critical piece of progress developing an AIDS vaccine. Photo credit: PATH/Evelyn Hockstein Nairobi, Kenya: Irene Anne Wangari and Agatha Nyawira work with blood samples at the Kenya AIDS Vaccine Initiative (KAVI) lab in Nairobi. Through its partnership with the International AIDS Vaccine Initiative, KAVI has facilitated significant breakthroughs in the research and trained world-class scientists and technicians who will continue to build on the research progress in Kenya. Photo credit: PATH/Evelyn Hockstein

After Secretary of State Hillary Clinton’s speech at the NIH earlier this week, GHTC asked our member organizations involved in HIV and AIDS why the US should continue to prioritize HIV and AIDS research. Here are answers from three of our members working on this issue: Elizabeth Glaser Pediatric AIDS Foundation: GHTC members stress the importance of prioritizing HIV and AIDS research in order to save lives around the world. Photo: Wendy Stone/PATH Discovering the medical interventions to prevent mother-to-child transmission of HIV (PMTCT) is one of the great success stories in the thirty-year fight against HIV and AIDS. But we cannot finish the job of eliminating pediatric AIDS worldwide without continued research. To implement the science that we do know, operations research is needed to address the global gaps in PMTCT coverage. Further clinical research is also needed to understand why approximately 60% of babies who are exposed to HIV from their mothers and receive no medical interventions still do not become infected. Answering this question could help in the development of an HIV vaccine that is safe and effective for children and adults, and provide lifetime immunity to the virus. International AIDS Vaccine Initiative: US support of HIV and AIDS research, including new HIV prevention tools, is vital to bringing an end to a pandemic that has taken and affected millions of lives in the US and worldwide, as well as cost the global economy billions of dollars. These investments also keep the US on the frontier of scientific innovation, as the lessons learned in trying to stop one most formidable foes ever encountered by scientists hold potential across many areas of medicine. Global Campaign for Microbicides/PATH: The generosity of the American people invested in HIV research can not only help to save the lives of poor people in other countries most greatly affected by HIV—but that same generosity can benefit the American people whose lives can also be saved by the same innovations. The world is a small place. As good global neighbors, prioritizing HIV research can help save the lives of poor people in not-so-distant lands. The same innovations in HIV treatment and prevention can save the lives of our neighbors much closer to home.

In this regular feature onBreakthroughs, we highlight some of the most interesting reads in global health research from the past week. Several cases of drug resistant tuberculosis (TB) are reported in India, underscoring the need for new treatment and prevention options. In related news, GHTC member Aeras enters into a partnership to develop new TB vaccines. GHTC member the American Society of Tropical Medicine and Hygiene urges against cuts to vital medical research that protects American troops from tropical diseases. New research could lead to the production of more affordable antimalarial drugs. GHTC member Medicines for Malaria Venture also seeks projects to propel malaria drug discovery. A Congressional delegation’s trip to see development projects in Tanzania included visits to global health projects. A candidate for the first-ever vaccine against hookworm enters into a clinical trial in Brazil.

Today, the GlobalPost’s “Global Pulse” blog posted a series of video interviews that GHTC conducted with prominent Americans and leading US health officials about why Americans should care about global health and research. On Tuesday, Secretary of State Hillary Clinton will be delivering a major speech on the HIV and AIDS pandemic at the National Institutes of Health. Clinton’s speech is expected to highlight US leadership in research and innovation for HIV and AIDS, particularly in developing treatment and prevention tools. Against that backdrop, the Global Health Technologies Coalition (GHTC), a Washington, D.C.-based advocacy group promoting global health research and development, interviewed prominent Americans and leading US health officials on why Americans should care about the issue. Here are the short responses from actress Whoopi Goldberg; Rep. Edward Markey (D-Mass.); US Food and Drug Administration Commissioner Dr. Margaret Hamburg; and Amie Batson, Deputy Assistant Administrator for Global Health at the US Agency for International Development. We’d also like to hear from you. In the Comments section, leave a note or send a link to a YouTube video explaining why Americans should care about global health research. Amie Batson on Why Americans Should Care about Global Health Research: FDA Commissioner, Margaret Hamburg: Representative Ed Markey (D-Mass): Whoopi Goldberg:

In this regular feature on Breakthroughs, we’ll highlight some of the most interesting reads in global health research from the past week. A bipartisan group of former USAID administrators calls on Congress to preserve funding for USAID, saying that the stakes are too high to cut investments in an agency that conducts such critical work across the globe. Bill Gates pushes for a stronger focus on innovation and stresses the benefits of foreign aid in the Washington Post. Gates also urges the G20 to adopt a transaction tax to raise money to fight global poverty.. Medical research is benefiting from creative new methods of funding. A CNN opinion piece highlights the need to protect funding for the President’s Emergency Plan for AIDS Relief (PEPFAR) to keep saving millions of lives around the globe and fight the global AIDS crisis. Secretary of State Hillary Clinton will focus on HIV and AIDS and the need for research for new tools during a speech at the NIH next week. USAID celebrates 50 years of saving lives around the globe. The GHTC examined the agency’s impressive support for global health R&D. Report urges regional collaboration on clinical trials to improve regulatory pathways and deliver health tools faster to the people who need them most.