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March 22, 2010

GlaxoSmithKline (GSK) and Pfizer today announced that they have joined the first Advance Market Commitment (AMC), a unique funding effort to bring pneumococcal vaccines to millions of children worldwide. The Global Health Technologies Coalition (GHTC) commends increased involvement in the AMC and calls on the United States to participate in innovative health financing mechanisms, including a future AMC, to maximize the life-saving potential of immunizations worldwide.

The first AMC was launched by the GAVI Alliance, the World Bank, the World Health Organization (WHO), the United Nations Children’s Fund (UNICEF), the Bill & Melinda Gates Foundation, and five national governments in June 2009. The introduction of a pneumococcal vaccine through the AMC is projected to prevent an estimated 900,000 deaths by 2015 and more than seven million deaths by 2030. In addition, the long-term price of a vaccine will be lowered from more than US$70 per dose to $3.50 under the AMC.

"Today’s landmark announcement promises to make new vaccines available affordably, where they are urgently needed, and faster than ever before. Through this AMC, and thanks to the political will demonstrated by donors and least developed nations and the participation of the pharmaceutical companies, prevention against the world’s biggest childhood killer is now within reach,” said GAVI Alliance CEO Dr. Julian Lob-Levyt.

These benefits underscore why the United States should consider engaging with future AMCs. The vaccine research pipeline is more promising than ever, with late-stage trials beginning on vaccines for diseases ranging from meningitis to malaria. It is crucial that this promising pipeline receives support from a wide range of partners to ensure success. US engagement in efforts to stimulate the development and delivery of immunizations is crucial to sustaining and building on this momentum. The Lantos-Hyde Act of 2008 directs the United States to invest in a future AMC, and the GHTC strongly urges policymakers to begin exploring how to engage in future AMC opportunities.

"As these new partnerships demonstrate, the pharmaceutical industry and other global health stakeholders are increasingly recognizing the AMC's role in spurring the development and delivery of vaccines for the developing world," said R. Gordon Douglas, Jr., MD, Executive Chairman of the Aeras Global TB Vaccine Foundation. "US support for AMCs would guarantee that recent successes in creating vaccines are sustained and extended going forward, saving the lives of even more children in the developing world."

Read the GAVI Alliance press release on the organization's website.