February 13, 2014

Research Roundup: What we’re reading this week

Senior Program Assistant

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

The University of Dundee in Scotland has developed a new antimalarial compound in their Drug Discovery Unit that has been selected by GHTC member Medicines for Malaria Venture (MMV) for further preclinical development. According to Dr. Kevin Read, co-project leader at University of Dundee, the compound will now undergo scale-up and further testing with the goal of entering human clinical trials in the next 18 months.

In a Q&A, PATH Technology Solutions Program Leader Anurag Mairal writes about product development and distribution challenges in global health. Mairal writes: “The biggest challenge with all of these great innovations is that they’re sometimes disconnected from the realities of what is needed on the ground in low-resource settings. The hurdles that innovative ideas face before they can become a sustainable global health solution are many.”

The US government has launched a new initiative to prevent, detect, and respond to infectious disease threats around the world. The initiative aims to improve security at infectious disease laboratories, strengthen immunization programs, and set up emergency response centers to deal with outbreaks.

The Lancet writes about the progress made in the tuberculosis drug pipeline, and the implications for future treatments against the disease. The author notes that while recent developments have been very promising, the health of the pipeline rests in nine candidates—all of which are still in preclinical development.