Research Roundup: A malaria-fighting toothpaste ingredient and new vaccine candidates for schistosomiasis and tuberculosis
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In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.
Research carried out in part by an artificially intelligent (AI) robot discovered that a common ingredient in toothpaste—triclosan—showed potential to
A National Institutes of Health (NIH)-funded schistosomiasis vaccine candidate will soon enter a Phase 1b clinical trial in an endemic region of Brazil. Researchers at Baylor College of Medicine, the George Washington University, and the René Rachou Institute will lead a double-blind, randomized, and controlled study in a group of 60 males and non-pregnant females with potential previous exposure to the parasite to test two different formulations of the vaccine. Schistosomiasis is the second most deadly parasitic infection in the world, affecting more than 200 million people worldwide. The vaccine being tested targets one of two parasite species, which accounts for one-third of all cases and one-half of schistosomiasis deaths worldwide. Many individuals previously treated for schistosomiasis are susceptible to reinfection, highlighting the importance of developing a safe and effective vaccine.