Breakthroughs Blog

Breakthroughs brings you stories of bright ideas and bold innovations in global health.

The Latest
Marissa Chmiola
Faces of Innovation: Dr. Geoffrey Siwo, researcher at University of Notre Dame

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Geoffrey Siwo, who we met at the American Society of Tropical Medicine and Hygiene Annual Conference, who develops mathematical models to accelerate product development at the University of Notre Dame in Indiana.

Recent

Research Roundup: flesh-eating bacteria treatment, Hepatitis C in Egypt, and access to compounds for drug discovery

Global Health Now took an in-depth look at the flesh-eating fungus mycetoma—which enters the body through cuts, and can result in swollen, deformed limbs—in a three-part series on this Untold Global Health Story of 2015.

GHTC
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PATH/Patrick McKern
Global Health Innovation Act has passed the House of Representatives

Last month, Representatives Albio Sires (D-NJ) and Mario Diaz-Balart (R-FL) introduced a new piece of legislation—the Global Health Innovation Act (H.R. 2241)—that would strengthen global health research and development (R&D) programming at the US Agency for International Development (USAID).

GHTC
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TB Alliance
Fruit-flavored drugs to saves kids’ lives: First correctly-dosed, child-friendly TB treatments developed

Early this month, GHTC member TB Alliance and its partners announced the creation of the first-ever appropriate, child-friendly tuberculosis (TB) medicine in the correct doses.

TB Alliance
TB Alliance
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A second chance for a TB research movement

In this guest post, Mike Frick, TB/HIV project officer at the Treatment Action Group (TAG), reflects on activist calls for greater investment in tuberculosis (TB) research and development (R&D) at the 46th Union World Conference on Lung Health and the stagnation of global TB R&D funding at a time of growing drug resistance.

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Research Roundup: Preterm birth indicators, African sleeping sickness treatment, and the world’s first dengue vaccine

Virginia Commonwealth University (VCU) received a grant from the Global Alliance to Prevent Prematurity and Stillbirth, a member of the GHTC, to study the human microbiome in search of biomarkers to predict preterm birth.

GHTC
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Transforming the lives of women and girls in sub-Saharan Africa and helping end AIDS through better HIV prevention research and development

In this guest post Tom Harmon, senior policy analyst at the International AIDS Vaccine Initiative (IAVI), and Anna Forbes, a globally recognized advocate for women’s HIV prevention needs, discuss a new piece proposing how HIV prevention research and development (R&D) for women and girls can better align with programs to improve their health and well-being.

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Research Roundup: the first kid-friendly TB treatment, enlisting smartphones to diagnose malaria, and promising new microbicides

GHTC member TB Alliance announced last week the creation of the first-ever child-friendly tuberculosis (TB) medicines, which are currently undergoing regulatory review by the World Health Organization and should be available in early 2016.

GHTC
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GHTC/Marissa Chmiola
Celebrating US leadership in global health R&D on Capitol Hill

On Wednesday evening, GHTC was joined on Capitol Hill by congressional champions—Congressman Adam Smith (WA-9) and Congresswoman Betty McCollum (MN-4)—and global health community members for a reception celebrating US leadership in global health research and development (R&D) and the launch of the 2015 G-FINDER report, which tracks investment in neglected disease R&D.

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Research Roundup: kid-friendly malaria medicine, Zika fever, priority review vouchers, and more

After four successful Phase 3 clinical trials enrolling more than 3,500 patients in 18 countries, the European Medicines Agency (EMA) has granted Pyramax® Granules, a pediatric malaria medicine, a positive opinion under Article 58—a mechanism through which the EMA reviews and issues a scientific opinion on products that are not intended for use in Europe.

GHTC
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What we’re thankful for in global health

It’s that time of year when Americans chow down on turkey with family and friends and express gratitude for the many things in life for which they are most thankful.

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