Breakthroughs Blog

Breakthroughs brings you stories of bright ideas and bold innovations in global health.

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Ansley Kahn
Research Roundup: NIH launches large TB prevention trial for people exposed to MDR-TB, Access to Medicine Index released, and diagnostic test could revive battle to eradicate yaws

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

Recent

PATH/Jennifer Fox
Germany announces second PDP funding round: What’s different and how does it impact global health R&D

Earlier this month, Germany’s Federal Ministry of Education and Research (BMBF) the renewal of the German funding program for product development partnerships (PDPs) conducting research and development (R&D) for health technologies to combat poverty-related and neglected diseases (PRNDs).

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CDC/National Institute of Allergy and Infectious Diseases
Research Roundup: an aerosol TB vaccine, a new coating for HIV/AIDS drugs, drug-resistant malaria, and more

Researchers at Tulane University successfully tested an experimental aerosol tuberculosis (TB) vaccine in monkeys, demonstrating that the candidate was more effective in protecting against infection than BCG—the only TB vaccine on the market.

GHTC
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GHTC
GHTC briefing highlights importance of health innovation to achieving global goals

With the Sustainable Development Goals (SDGs) freshly adopted, the Global Health Technologies Coalition (GHTC) gathered representatives from the private, public, and nonprofit sectors on Capitol Hill this past Wednesday to discuss what it will take to achieve the global goals.

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The R&D agenda and how it addresses access to vaccines

In this guest post, Dr. Jayasree K. Iyer—Chief Scientific Officer at the Access to Medicine Foundation—writes about the findings from their newest study, which examines the current state of the vaccine pipeline and how large pharmaceutical companies are considering access to these products.

Access to Medicine Foundation
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CDC/Dr. Scott Smith
Research Roundup: an HIV/AIDS vaccine candidate, inflatable incubator for premature babies, and US government R&D

Dr. Robert Gallo co-discovered the HIV virus and subsequently led the development of the first HIV/AIDS blood test.

GHTC
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Tackling hidden hunger through innovation

When most people think of hunger, they think of a lack of food—a nation suffering from crop failure and famine, or a family that can’t afford to put enough food on the table.

GHTC
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CDC
Research Roundup: TB R&D, malaria in pregnancy, and treatments for filarial diseases

A new briefing paper from the Infectious Diseases Society of America Center for Global Health Policy explores the state of tuberculosis (TB) research and development (R&D) including challenges for products currently in the pipeline and gaps in TB research.

GHTC
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Why we need research to detect, prevent, and ultimately, eliminate parasitic diseases

In this guest post, Dr. Monica Parise—deputy director for program and science—and Dr. Larry Slutsker—director of the Division of Parasitic Disease and Malaria—at the US Centers for Disease Control and Prevention (CDC) Center for Global Health—discuss the role of research in advancing efforts to detect, prevent, and eliminate parasitic diseases.

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Research Roundup: genetic protection against malaria, the vaccine pipeline, and counterfeit drugs and the FDA

A new study conducted by the Malaria Genomic Epidemiology Network (MalariaGEN)—a community of researchers across malaria-endemic regions—reveals a formerly unknown genetic variations that make people less susceptible to malaria.

GHTC
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PATH/Evelyn Hockstin
Research Roundup: a promising Ebola treatment, access to drugs for NCDs, a new approach to treating a deadly bacterium, and the perception of breakthrough drugs

The US Department of Health and Human Services (HHS) is partnering with New York–based Regeneron Pharmaceuticals, Inc. for the development of an Ebola treatment.

GHTC
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PATH/James Gathaney
Research Roundup: antibiotic and reproductive health R&D, leadership at the FDA, and a potential new strain of dengue fever.

The US Department of Health and Human Services (HHS) announced last week a partnership with pharmaceutical company AstraZeneca for the research and development (R&D) of antibiotics.

GHTC
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PATH/Patrick McKern
Female condoms: the feel and shape of things to come

Take a stroll through any pharmacy and you’ll see shelves stacked with male condoms of many varieties, but look for a female condom and you aren't likely to find one for sale.

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Advocacy and partnerships for HIV/AIDS prevention for women: A post from Durban, South Africa

Sitting halfway around the world from my office in Washington, DC, looking out my Durban hotel window at the Indian Ocean, I am reminded just how small and interconnected our world really is.

GHTC
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Research Roundup: HIV/AIDS self-testing and advances in dengue fever and sleeping sickness R&D

A new study suggests that with basic training, individuals can learn to accurately and safely test themselves for HIV/AIDS.

GHTC
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To meet the global goals, UN must include health R&D indicators in SDG framework

Later this month global leaders are poised to approve the Sustainable Development Goals (SDGs), but a new report commissioned by a leading group of health nonprofits including GHTC warns that the SDG targets will not be achieved without the development and introduction of new and improved health technologies to address the health needs of the world’s poorest people.

GHTC
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PATH/Eric Becker
Research Roundup: injectable HIV treatment, the role of health technologies in reaching SDGs, PrEP showing promise, and more

An injectable HIV/AIDS treatment that could offer HIV-positive individuals an option other than taking daily pills is entering late-stage clinical-trials.

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Pipeline report points toward nascent progress in the fight against tuberculosis

In this guest post, Lindsay McKenna, TB/HIV project officer at GHTC member Treatment Action Group (TAG), writes about a newly released report examining advancements in tuberculosis (TB) research and development (R&D).

Treatment Action Group
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PATH/Aaron Joel Santos
Research Roundup: priority review vouchers, diagnosing drug resistance, and oral and universal flu vaccines

Pharmaceutical company AbbVie is paying United Therapeutics US$350 million for its priority review voucher (PRV)—which expedites the US Food and Drug Administration’s (FDA) review of a product by four months—and EP Vantage speculates on their motive.

GHTC
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Research Roundup: a rapid diagnostic for three hemorrhagic fevers, a MERS vaccine to be tested in humans, and advances in R&D for HIV treatments

A new paper-based diagnostic can test for Ebola, dengue, and yellow fever in just ten minutes without running water, electricity, lab equipment, or highly-trained personnel.

GHTC
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Research Roundup: combatting malaria with forensics, detecting counterfeit drugs out of a suitcase, and preventing the flu without a vaccine

Luminol has long been used to detect blood at crime scenes, as it glows bright blue when it comes into contact with the blood protein hemoglobin, however, new research suggests that it could be repurposed to fight malaria in humans.

GHTC
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