Global pipeline for neglected diseases
All data: Policy Cures Research. R&D Pipeline Tracker. 2019. Available from: https://www.pipeline.policycuresresearch.org.
Funding for neglected disease R&D
R&D $286 billion global spending on all health R&D: Røttingen, J-E, Regmi, S, Eide, M et al. Mapping of available health research and development data: what’s there, what’s missing and what role is there for a global observatory. Lancet. 2013; 383:1286–1307. [Data is for total global spending on health R&D in 2009 purchasing power parity-adjusted dollars, inflation adjusted to 2019 dollars.]
$3.9 billion global spending on neglected disease R&D/Neglected disease R&D by sector: Chapman N, Doubell A, et al. Neglected Disease Research and Development: Where to Now?. G-FINDER | 2020. Sydney: Policy Cures Research; 2021.
Return on investment in global health R&D
Antiretroviral therapies have prevented 12.1 million AIDS-related deaths: UNAIDS. Seizing the moment: Tackling entrenched inequalities to end pandemics. Geneva: UNAIDS; 2020.
A new child-friendly malaria medicine has saved 860,000 lives: Medicines for Malaria Venture webpage. Homepage – Achievements. https://www.mmv.org/. Accessed April 5, 2021.
$.89 of every US dollar: Policy Cures Research, Global Health Technologies Coalition. Return on innovation: Why global health R&D is a smart investment for the United States. Sydney: Policy Cures Research; 2017.
€.80 of every euro: Policy Cures, Deutsche Stiftung Weltbevoelkerung. Saving lives: Making the case for European investment in poverty-related and neglected disease R&D. Sydney: Policy Cures; 2016.
Anti-malaria efforts are projected to provide: Purdy M, Robinson M, Wei K, Rublin D. The economic case for combating malaria. American Journal of Tropical Medicine and Hygiene, 2013; 89(5):819–23.
US government investment in global health R&D from 2007–2015: Policy Cures Research, Global Health Technologies Coalition. Return on innovation: Why global health R&D is a smart investment for the United States. Sydney: Policy Cures Research; 2017.
$26 million invested in polio vaccine R&D: Thompson KM, Tebbens RJ Retrospective cost-effectiveness analyses for polio vaccination in the United States. Risk Anal. 2006; 26(6):1423–40.
Every $1 invested in HIV vaccine R&D: Hecht R, Jamison DT. Vaccine research and development assessment paper In: Lomborg B, ed. Rethink HIV: smarter ways to invest in ending HIV in sub-Saharan Africa. New York: Cambridge University Press, 2012; 299–320.
Meningitis A vaccine estimated to have saved nearly $9 billion: Ozawa S, Clark S, Portnoy A, et al. Estimated economic impact of vaccinations in 73 low- and middle-income countries, 2001–2020. Bulletin of the World Health Organization. 2017; 95(9): 629-638.
The 2014 Ebola epidemic cost the US $3 billion: Cost of the Ebola Epidemic |Ebola Hemorrhagic Fever |US Centers for Disease Control and Prevention [Internet]. [cited 2017 Mar 22]. Available from: https://www.cdc.gov/vhf/ebola/outbreaks/2014-west-africa/cost-of-ebola.html.
The 2014 Ebola epidemic cost the EU $1.2 billion: EU response to the Ebola outbreak | European Commission [Internet]. [cited 2017 July 9]. Available from: https://ec.europa.eu/europeaid/regions/africa/west-africa/ebola-response_en.
Every $1 invested in the ACT Accelerator: Adhanom Ghebreysus, Tedros. “WHO Director-General's opening remarks at the High-Level Finance Ministries’ Meeting for the ACT Accelerator.” 29 Jan 2021.
By 2050, antimicrobial resistance could lead to 10 million deaths: Review on Antimicrobial Resistance. Antimicrobial Resistance: Tackling a Crisis for the Health and Wealth of Nations. 2014.
1 billion people affected by neglected diseases: World Health Organization (WHO). Investing to Overcome the Global Impact of Neglected Tropical Diseases: Third WHO Report on Neglected Tropical Diseases. Geneva: WHO; 2015.
6 million annual deaths from neglected diseases: Institute for Health Metrics and Evaluation (IHME). Global Burden of Disease Study 2010 (GBD 2010) Results by Cause and by Region 1990-2010. 2013.
218 million women have unmet family planning needs: Adding it Up: Investing in Contraception and Maternal and Newborn Health, 2019. New York: Guttmacher Institute, 2019.
Critical US role in global health R&D
All data: Policy Cures Research, Global Health Technologies Coalition. Return on innovation: Why global health R&D is a smart investment for the United States. Sydney: Policy Cures Research; 2017.
Top public funders of neglected disease R&D
Calculated based on 2019 neglected diseases investment data from: Policy Cures Research. G-FINDER data portal. Sydney: Policy Cures Research; 2020 - https://www.policycuresresearch.org/g-finder/