From Breakthroughs Blog:

 
Research Roundup: FDA approves Ebola vaccine, experimental vaccine patch leaves a mark, masquerading virus for vaccine R&D

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Congress passes final FY20 spending packages marked by continued support for global health R&D
This week, months of tense negotiation between leaders in the Democratically-controlled US House of Representatives, the Republican-held Senate, and the White House concluded with the passage of two massive spending packages encompassing all federal government spending for fiscal year (FY) 2020 —nearly three months behind schedule.
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Faces of Innovation: Dan Littlefield, researcher at Modality Solutions

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dan Littlefield, who we met at the American Society of Tropical Medicine and Hygiene Annual Conference. Dan co-founded a cold-chain engineering company that worked with the Centers for Disease Control and Prevention and the Biomedical Advanced Research and Development Authority to distribute Ebola vaccines for clinical trials in Sierra Leone.

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Research Roundup: GSK seeks licensing for child-friendly HIV pill, reports say TB R&D funding still falling short, and Gavi to stockpile Ebola vaccines

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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A year in review: The global health innovation stories that shaped 2019

As the year comes to a close, we are taking a look back at the top global health innovation stories and news that shaped 2019.

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Research Roundup: Once-a-month birth control pill, experimental typhoid fever vaccine, and release of 2019 World Malaria Report

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: child-friendly HIV drugs, trial shows two Ebola treatments significantly reduce mortality, and study shows for babies born with HIV to start treatment right away

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Faces of Innovation: Hannah Wu, researcher at Brown University

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Hannah Wu, who we met at the American Society of Tropical Medicine and Hygiene (ASTMH) Annual Conference, who is working to develop vaccines against the neglected tropical disease schistosomiasis at Brown University.

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Explainer: the Nagoya Protocol and its impact on global health R&D

The World Health Organization recently announced that at its upcoming Executive Board meeting in February member states will discuss challenges and issues in implementing the Nagoya Protocol—a legal framework that governs the access to and benefits gained through the sharing of genetic resources including human and animal DNA, plants, and pathogens. As these discussions heat up, GHTC is taking a brief look at what the Nagoya Protocol is, how it impacts global health R&D, and what’s next for the future of this framework.

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Faces of Innovation: Dr. Rohit Ramchandani, researcher at the Johns Hopkins University and the University of Waterloo

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Rohit Ramchandani, who we met at the American Society of Tropical Medicine and Hygiene Annual Conferenc. Dr. Ramchandani does research to innovate global treatment options for childhood diarrhea at the Johns Hopkins School of Public Health in Baltimore, Maryland and the University of Waterloo. 

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Faces of Innovation: Dr. Vinayak Joshi, researcher at VisionQuest Biomedical

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Vinayak Joshi, who we met at the American Society of Tropical Medicine and Hygiene Annual Conference. Dr. Joshi is working on a diagnostic for cerebral malaria with support from the National Institute of Allergy and Infectious Diseases.

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Research Roundup: Lab on wheels could improve outbreak response, new chemical formulation for bednets shows promise, and experimental HIV vaccine elicits broadly neutralizing antibodies

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Faces of Innovation: Dr. Aileen Marty, researcher at Florida International University

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Aileen Marty, who we met at the American Society of Tropical Medicine and Hygiene Annual Conference. Dr. Marty works at Florida International University and serves on the President’s Advisory Council for Combating Antibiotic-Resistant Bacteria.

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Faces of Innovation: Dr. Mohammad Nuhu Amin, researcher at icddr,b

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Mohammad Nuhu Amin, who we met at the American Society of Tropical Medicine and Hygiene Annual Conference. Dr. Amin researches sanitation and diarrheal diseases with support from the United States Agency for International Development.

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Faces of Innovation: Dr. James Mutunga, researcher at the US Army Medical Research Directorate

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. James Mutunga, who we met at the American Society of Tropical Medicine and Hygiene (ASTMH) Annual Conference, who does research on developing and testing new methods of controlling vector-borne diseases as well as pathogen surveillance in arthropod disease vectors at the US Army Medical Research Directorate-Africa in Kisumu, Kenya. 

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Faces of Innovation: Dr. Katie Button-Simons, researcher at University of Notre Dame

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Katie Button-Simons, who we met at the American Society of Tropical Medicine and Hygiene Annual Conference, who does research on drug-resistance in malaria at the University of Notre Dame in Indiana.

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Faces of Innovation: Dr. Mary Kamb, researcher at CDC

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Mary Kamb, who we met at the American Society of Tropical Medicine and Hygiene Annual Conference, who leads the Elimination and Control Epidemiology team at the Centers for Disease Control and Prevention, Division of Parasitic Diseases and Malaria.

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Faces of Innovation: Dr. Peter Hotez, researcher at Baylor College of Medicine

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Peter Hotez, who we met at the American Society of Tropical Medicine and Hygiene (ASTMH) Annual Conference, who does research to develop vaccines for neglected tropical diseases as professor and Dean of the National School of Tropical Medicine at the Baylor College of Medicine in Houston, Texas. 

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Faces of Innovation: Dr. Christine Petersen, researcher at University of Iowa

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Christine Petersen, who we met at the American Society of Tropical Medicine and Hygiene Annual Conference, who researches how infectious diseases transmit between animals and people at the University of Iowa.

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Faces of Innovation: Mohammad Ariful Islam, researcher at icddr,b

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Mohammad Ariful Islam, who we met at the American Society of Tropical Medicine and Hygiene Annual Conference. Ariful researches influenza in Bangladesh with funding from the US Centers for Disease Control and Prevention.

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Faces of Innovation: Dr. Heinz Weidenthaler, researcher at Bavarian Nordic

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Heinz Weidenthaler, who we met at the American Society of Tropical Medicine and Hygiene (ASTMH) Annual Conference, who developed a smallpox and monkeypox vaccine with Bavarian Nordic.

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Faces of Innovation: Dr. Geoffrey Siwo, researcher at University of Notre Dame

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Geoffrey Siwo, who we met at the American Society of Tropical Medicine and Hygiene Annual Conference, who develops mathematical models to accelerate product development at the University of Notre Dame in Indiana.

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Faces of Innovation: Dr. Joseph Tucker, researcher at University of North Carolina

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Joseph Tucker, who we met at the American Society of Tropical Medicine and Hygiene Annual Conference, who uses grassroots methods to influence health messages and interventions in local communities, at the University of North Carolina.

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Faces of Innovation: Dr. Mark Kortepeter, researcher at University of Nebraska

Faces of Innovation—a new GHTC project that features scientists on the front lines of research and development on new global health tools and technologies—profiles Dr. Mark Kortepeter, who we met at the American Society of Tropical Medicine and Hygiene (ASTMH) Annual Conference, who does research on emerging infectious diseases at the University of Nebraska in Lincoln.

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Research Roundup: the threat of antibiotic resistant infections, J&J Ebola vaccine roll out in DRC, and Merck Ebola vaccine granted marketing approval by European Commission

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: First new HIV strain discovered in 19 years, Takeda vaccine for dengue, and researchers use drones to pilot a new tool to fight malaria

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: New Zika blood test, TB vaccine shows sustained protection, first Lassa fever vaccine set for trial by year's end

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Strain of polio eradicated, NIH & Gates Foundation partner to find genetic cures for HIV & sickle cell, and G20 health ministers issue declaration

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Play: TRICK or TREATment?

To enjoy a bit of fun and mischief this Halloween, we’ve created a game, TRICK or TREATment, to test our readers’ knowledge of global health technologies.

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Research Roundup: Merck Ebola vaccine approved by European regulators, TB funding gap persists, and new NTD detected in Brazil

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Global Fund replenishment, FDA allows marketing of first rapid Ebola test, and NIH to launch influenza vaccine research centers

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Bacteria-infected mosquitoes to fight dengue, BARDA to fund Marburg and Ebola vaccines, and saliva test to diagnose malaria

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Antibody to combat malaria, BARDA to advance Ebola treatment, and UHC High-Level Meeting

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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What’s next for universal health coverage?

United Nations members unanimously adopted a high-level political declaration on universal health coverage (UHC), but while the adoption of the declaration is welcome news, in many ways it represents a starting point for the next phase of UHC, in which the thornier issues of financing, follow through, and accountability will rise to the forefront.

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GHTC brings a global perspective to the Rally for Medical Research

A crisp chill hung in the air one early morning last week as members of the GHTC team stepped up the stairs adjoining the newly refurbished Apple Carnegie Library in Washington, DC, to pose for a photo with more than one hundred fellow research and development (R&D) advocates from across the country.

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Congressional briefing highlights Department of Defense’s long war against a surprising enemy: malaria

Most Americans think of malaria as a disease that only threatens people in far-off nations. But with American military personnel deployed in countries all around the globe, malaria remains an ongoing threat to the health of our servicemembers and, by extension, our military readiness. 

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Research Roundup: Scientists release sterile mosquitoes in Burkina Faso, Themis raises $44 million for phase 3 chikungunya vaccine trial, and Merck's Ebola vaccine tees up FDA date

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Kenya 3rd country to roll out malaria vaccine, scientists gene-edit stem cells to treat HIV, and an affordable new test for dengue

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: 'Highly effective' way to kill malaria parasite, a mobile program to get TB patients to take their pills, and radiating mosquitoes to stop dengue fever outbreak

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Thyme oil and corn starch used as larvicide, Gates Foundation grants for a universal flu vaccine, and Gavi calls on donors

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research in action in Uganda

Last week GHTC led a learning trip with US Congressional staff to Uganda to see first hand the impact of US government funding for global health R&D. Check out our favorite moments from the week.

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Observations and insights on the history and future of health innovation at USAID

To reflect on USAID’s decades of work in global health innovation and the future of these efforts, GHTC held a dialogue in early August featuring USAID Chief of Staff Bill Steiger, as well as representatives from USAID’s Global Health Bureau and nonprofit and private sector partners. Here are some of our favorite observations and insights from the discussion.

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Research Roundup: WHO releases findings from malaria eradication report, two-month HIV injection could be on its way, and refrigerator to protect vaccines against power outages

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: The first chlamydia vaccine passed a major test, a new drug approved for drug-resistant tuberculosis, and two new Ebola treatments prove highly effective in the DRC

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: A portable “cholera detection lab," Sabin acquires rights to develop Ebola and Marburg vaccines, and Uganda starts largest-ever Ebola vaccine trial

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: A 'Google' for biomedical data, alarming surge in drug-resistant HIV, and CEPI partners with Valneva to develop Chikungunya vaccine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: WHO recommends dolutegravir as the first-choice HIV treatment, an arm implant that may one day protect against HIV, and malaria drugs failing in Southeast Asia

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Wiping out mosquitoes on two Chinese islands, betting on biometrics to boost vaccination rates, and J&J to test HIV vaccine in US and Europe

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: a two-drug HIV treatment found equally effective as three drugs, experimental Ebola treatments show promise in lab study, and WHO upgrades list of essential diagnostic tests

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: GARDP to develop 5 new treatments for antibiotic resistant infections by 2025, researchers eliminated HIV from DNA of infected mice, and G20 leaders commit to advance global health

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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G20 leaders commit to advance global health, with partial recognition of R&D’s role

On Saturday, heads of state and government from the world’s leading economies concluded this year’s G20 Summit in Osaka, Japan by issuing a declaration committing to advance global health.

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Research Roundup: NIH launches large TB prevention trial for people exposed to MDR-TB, Access to Medicine Index released, and diagnostic test could revive battle to eradicate yaws

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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3 takeaways from the inaugural Global Health Security Conference

Last week, the Australian government and the Indo-Pacific Centre for Health Security convened practitioners, researchers, educators, and decision-makers across the fields of public health, medicine, veterinary science, agriculture, government, defense, and anthropology for the first Global Health Security Conference in Sydney to examine the progress made to date in strengthening health systems and to identify gaps and opportunities for enhancing the international community’s ability to respond more efficiently and effectively to future health crises.

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Research Roundup: Rotavirus vaccine may help protect against Type 1 diabetes, 1 million child-friendly TB courses ordered since 2016, and Trump orders agencies to trim advisory panels

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Contraceptives and HIV trial, identification of protective antibodies may be key to malaria vaccine, and Drug Transparency Observatory launched In France

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: FDA advisory panel recommends approval of TB Alliance's TB treatment, innovation in women's health, and British syringe-free vaccine maker set to shake up the industry

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Saving two lives, not just one: medicines for malaria during pregnancy

An estimated 125 million pregnancies around the world are at risk from malaria annually. For both mother and baby, the disease is potentially life-threatening and babies that do survive are often born with low birth weight, which is associated with negative impact on development.

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Research Roundup: An experimental Ebola cure may also protect against Nipah virus, gender inequality in clinical trials, and FDA authorizes first Zika diagnostic test for marketing

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Four Takeaways from WHA 72

Against a backdrop of mounting global health challenges, the 72nd World Health Assembly (WHA) convened last week, with politicians, philanthropists, business executives, and civil society leaders all descending upon Geneva. GHTC was on the scene—attending side events, technical briefings, and following the official agenda. Here are our top four takeaways from this year’s assembly.

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Research Roundup: WHO Foundation, Algeria and Argentina declared malaria free, and scientists break away from 'cold chain' to deliver vaccines

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: WHO unveils online resource to guide neglected disease R&D, major funding announcements for snakebite research, and TB Alliance awarded grants to develop TB drug candidates

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Warning to address drug-resistant TB, a new Ebola vaccine strategy in DRC, and FDA takes step to bolster research on pregnant and lactating women

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Innovating the way towards UHC at WHA

Universal health coverage (UHC) will take center stage at the World Health Assembly later this month. While there are many building blocks to achieve UHC, one integral pillar that is too often overlooked is innovation—the creation of new and improved drugs, vaccines, and diagnostic tools. Global health research and development is indispensable in delivering on the vision of quality health for all.

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Gamifying global health innovation

GHTC held a Game changers in global health game night on Capitol Hill to educate Congressional staffers about the impact of US leadership in global health research and development (R&D). Our guests ate, drank, played games, and learned how US investments in global health R&D not only saves lives around the world, but also generates benefits here at home in the United States. Here are some of our favorite photos.

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Research Roundup: Study finds drugs stop HIV transmission, polio endgame strategy includes new technologies and vaccines, and FDA approves first ever vaccine for dengue fever

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: World's first malaria vaccine, how to shape research to advance global health, and lotion that protects from malaria

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Members of Congress push back at President’s budget cuts to global health research

The Trump administration’s budget request for fiscal year 2020 (FY20) includes cuts that—if enacted—would hamstring the research and development (R&D) of new global health technologies. Since the release of the budget request in early March, however, lawmakers from both parties have expressed their commitment to shielding critical funding strings from the president’s scissors.

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Research Roundup: AI advancing drug development, malaria vaccine tested in large clinical trial, and first-in-human universal flu vaccine trial

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: WHO emergency panel meets about Ebola in DRC, new study reveals HIV vulnerabilities, and how Global Health Investment Fund is revolutionizing impact investing

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Tiny guillotine decapitates mosquitoes to fight malaria, new antibody approach to tackling Ebola, and faster and cheaper test to detect Zika

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Contraceptive jewelry may be new family planning option, microneedle technology receives green light, and aspirin to fight TB

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: the cost of wiping out TB, a global hub for AMR, and US begins $10 million vaccine project against Marburg virus

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Study finds safer & shorter treatment for Chagas, Trumps budget proposes cuts to biomedical research, and FDA accepts new drug application for pretomanid in combination TB regimen

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: WHO transformations, new funding model for health needed, and HIV reported cured in second patient

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: CEPI invests in vaccine printer tech, new bednet strategy to fight malaria, and Themis' chikungunya vaccine nabs FDA Fast Track

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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President signs spending bill boosting funding for global health

On February 15, President Trump signed into law a bipartisan spending bill—averting another partial government shutdown and ensuring full-year funding for the government for the remainder of fiscal year 2019. The months-long saga ended with some great news for global health and research and development.

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Research Roundup: Pregnant women in DRC to be given Ebola vaccine, releases of genetically modified mosquitoes in high-security lab, and CRISPR may help against viruses for which no vaccine exists

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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WHO EB moves forward actions on budget, access to medicines, and AMR R&D

The 2019 global health multilateral calendar kicked off as it always does with the World Health Organization (WHO) Executive Board (EB) meeting in late January in Geneva. This year’s session featured a packed agenda with significant implications for research and development.

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Research Roundup: SFOPs funding for FY19, Lassa fever outbreak in West Africa, and new TB drug may shorten treatment time

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: New funding partnership to develop drugs for leishmaniasis, an atlas of HIV mutations could improve vaccine design, and a high-tech pill could end drug injections

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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State of the Union HIV pledge links a “once-distant dream” to “scientific breakthroughs”

On February 5, President Trump delivered his second State of the Union address. Among the long list of policy proposals and pledges in the speech was one of great interest to the global health research community—an announcement of a new whole-of-government plan to eliminate HIV transmission in the United States by 2030.

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Research Roundup: DNA from single mosquito sequenced, Pandemic Response Box to boost research, and experimental Ebola treatment proves safe in adults

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Ebola found in West African bat for the first time, global health R&D money reaches record high, and temperature-stable TB vaccine enters clinical testing

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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How the partial government shutdown is affecting global health, R&D

As the partial government shutdown stretches into a fifth week – the longest in United States history – news of its impact on agencies essential to global health broadly, and research and development in particular, is taking clearer shape.

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As America leads, other nations step up to fund R&D to combat neglected disease threats

The US government has long played an indispensable role in driving global health progress as the world’s leading funder of research and development (R&D) for new vaccines, treatments, and other tools to fight neglected diseases.

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Research Roundup: Single-dose drug for recurrent malaria, long-acting contraceptive self-administered via microneedles, and fast diagnosis of viruses

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Single-dose Ebola drug, mosquito birth control, and new TB treatment

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Research Roundup: Vaccines without chemicals, FDA fast track for Vanelva's chikungunya vaccine, and Marburg virus found in bats in West Africa

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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