Breakthroughs Blog

Breakthroughs brings you stories of bright ideas and bold innovations in global health.

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Marissa Chmiola
Observations and insights on the history and future of health innovation at USAID

To reflect on USAID’s decades of work in global health innovation and the future of these efforts, GHTC held a dialogue in early August featuring USAID Chief of Staff Bill Steiger, as well as representatives from USAID’s Global Health Bureau and nonprofit and private sector partners. Here are some of our favorite observations and insights from the discussion.

Recent

Seven takeaways on the post-2015 negotiations

Trying to navigate and understand the post-2015 negotiations can be a challenge, so to help add some clarity, last week the Global Health Technologies Coalition (GHTC) convened a panel of experts to help explain the ongoing debates and where the negotiations stand and how health innovation is reflected in the agenda.

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PATH/Lesley Reed
Research Roundup: leadership at USAID, investments in global health research at US universities, and measuring the impact of open innovation

United States President Barack Obama announced last week his intent to nominate Gayle Smith, senior director for Development and Democracy at the National Security Council, to lead the US Agency for International Development (USAID).

GHTC
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PATH/Evelyn Hockstein
Research Roundup: resistance to antimalarials in Africa, R&D for bioterrorist attacks, and more

Scientists at the London School of Hygiene and Tropical Medicine have identified a mutation in Plasmodium falciparum—the parasite responsible for the majority of fatal cases of malaria—that makes the parasite more resistant to quinine and artemisinin, the leading antimalarials worldwide.

GHTC
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Photo courtesy of the David and Lucile Packard Foundation.
Could climate change lead to chikungunya? Examining the link between climate change and health

Polar bears and penguins aren’t the only species threatened by climate change.

GHTC
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PATH/Patrick McKern
Research Roundup: publication of clinical trial results, the establishment of an African CDC, and more

The World Health Organization (WHO) released a statement last week calling for the publication of all data from clinical trials for drugs, vaccines, and medical devices.

GHTC
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PATH/Jennifer Fox
Research Roundup: research capacity building in Africa, lessons learned from the Ebola outbreak, and top health officials in the United States tell Congress to “think globally”

A new initiative seeks to develop research capacity within Africa and create a regional hub with the ability to determine research needs and award grants.

GHTC
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PATH/Gabe Bienczycki
Research Roundup: India to expand list of essential medicines, China’s emerging leadership in the pharmaceutical industry, WHO paves the way for hepatitis C generics, and more

India is expected to add all of the drugs currently used in the government’s HIV/AIDS and tuberculosis (TB) control programs to its list of essential medicines within the next six months.

GHTC
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PATH/Evelyn Hockstein
GHTC briefing highlights importance of global health innovation in protecting US and world from threats like Ebola

On Thursday, March 26, 2015, the Global Health Technologies Coalition (GHTC) launched its sixth annual policy report titled Meeting the challenge, seizing the opportunity: US leadership can advance global health R&D with a luncheon and panel discussion on Capitol Hill.

GHTC
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CDC
Research Roundup: clinical trials for experimental Ebola vaccines, genetic traits that affect malaria risk, and progress toward a hookworm vaccine

The National Institute of Allergy and Infectious Diseases (NIAID) announced last week that two experimental Ebola vaccines appear to be safe for widespread use, based on early results of clinical trials in Liberia.

GHTC
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PATH/Gabe Bienczycki
Research Roundup: new discoveries in the search for a malaria vaccine and tuberculosis treatment and lessons from the Ebola epidemic

A team of scientists at Heinrich-Heine Universität Düsseldorf have identified a potential new player in the fight against tuberculosis (TB).

GHTC
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US Centers for Disease Control and Prevention
Fighting for the future: Why we must come together to fight antibiotic resistance around the globe

I am pleased to have the opportunity to write about what is perhaps today’s most vexing public health challenge—the growing threat of antibiotic resistance.

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PATH/Gabe Bienczycki
Research Roundup: discoveries in malaria research, remaining barriers to the development of an Ebola vaccine, and a diagnostic for maternal survival

Scientists at Karolinska Institutet in Sweden have identified the protein that explains why people with blood type O are protected from coma and death resulting from severe cases of malaria.

GHTC
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PATH/Lesley Reed
Research Roundup: Leadership shifts at USAID, new discoveries in tuberculosis research, an emerging model for nonprofit pharmaceutical companies, and more

The US Agency for International Development (USAID) announced last week that Ariel Pabos-Mendez, the assistant administrator for Global Health, will serve as the coordinator for Child and Maternal Survival.

GHTC
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PATH/Patrick McKern
Research Roundup: Progress towards a vaccine for HIV, a rapid diagnostic and experimental drug for Ebola, and congressional support for global health research

A new compound has successfully protected monkeys from HIV, according to a study published in Nature last week.

GHTC
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PATH/Heng Chivoan
Research Roundup: A new drug for tuberculosis, contraceptive research and development, drug-resistant malaria, and more

The TB Alliance, a member of the Global Health Technologies Coalition, announced last week that it will be starting Phase 1 clinical trials for a new tuberculosis (TB) drug candidate.

GHTC
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PATH/Wendy Stone
Research Roundup: A promising malaria vaccine, a virulent new form of HIV, climate change, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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DNDi/João Roberto Ripper
Chagas disease: A silent kiss and a neglected killer

Valentine’s Day seems like a fitting occasion to shine some needed light on a disease that can begin with a late-night “kiss” but ends with a broken heart.

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PATH/Wendy Stone
Research Roundup: FDA Commissioner to step down, a Grand Challenge for neglected diseases, funding for reproductive health research and development, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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WHO Executive Board agrees on set-up of pooled fund for global health R&D

In this guest post, Alexandra Heumber—head of policy affairs at the Drugs for Neglected Diseases initiative—discusses actions taken during the World Health Organization (WHO)’s Executive Board meeting which could impact financing for the research and development (R&D) of new health technologies for developing countries.

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Obama Administration’s FY2016 budget presents mixed outlook for global health R&D

On Monday the White House turned heads by releasing, for the first time since 2010, an on-time budget. Overall the White House presented a mixed outlook for global health research and development (R&D).

GHTC
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