From Breakthroughs Blog: Vaccine

 
PATH/Satvir Malhotra
Research Roundup: Contraceptives and HIV trial, identification of protective antibodies may be key to malaria vaccine, and Drug Transparency Observatory launched In France

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Matthew Dakin
Research Roundup: FDA advisory panel recommends approval of TB Alliance's TB treatment, innovation in women's health, and British syringe-free vaccine maker set to shake up the industry

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Georgina Goodwin
Research Roundup: WHO Foundation, Algeria and Argentina declared malaria free, and scientists break away from 'cold chain' to deliver vaccines

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Gabe Bienczycki
Research Roundup: WHO unveils online resource to guide neglected disease R&D, major funding announcements for snakebite research, and TB Alliance awarded grants to develop TB drug candidates

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Wendy Stone
Research Roundup: Study finds drugs stop HIV transmission, polio endgame strategy includes new technologies and vaccines, and FDA approves first ever vaccine for dengue fever

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Doune Porter
Research Roundup: World's first malaria vaccine, how to shape research to advance global health, and lotion that protects from malaria

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Gabe Bienczycki
Research Roundup: AI advancing drug development, malaria vaccine tested in large clinical trial, and first-in-human universal flu vaccine trial

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Satvir Malhotra
Research Roundup: WHO emergency panel meets about Ebola in DRC, new study reveals HIV vulnerabilities, and how Global Health Investment Fund is revolutionizing impact investing

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Mike Wang
Research Roundup: Tiny guillotine decapitates mosquitoes to fight malaria, new antibody approach to tackling Ebola, and faster and cheaper test to detect Zika

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Mike Wang
Research Roundup: CEPI invests in vaccine printer tech, new bednet strategy to fight malaria, and Themis' chikungunya vaccine nabs FDA Fast Track

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Algy Amad
Research Roundup: Pregnant women in DRC to be given Ebola vaccine, releases of genetically modified mosquitoes in high-security lab, and CRISPR may help against viruses for which no vaccine exists

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Wendy Stone
Research Roundup: New funding partnership to develop drugs for leishmaniasis, an atlas of HIV mutations could improve vaccine design, and a high-tech pill could end drug injections

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Patrick McKern
Research Roundup: DNA from single mosquito sequenced, Pandemic Response Box to boost research, and experimental Ebola treatment proves safe in adults

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Patrick McKern
Research Roundup: Ebola found in West African bat for the first time, global health R&D money reaches record high, and temperature-stable TB vaccine enters clinical testing

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Satvir Malhotra
Research Roundup: Vaccines without chemicals, FDA fast track for Vanelva's chikungunya vaccine, and Marburg virus found in bats in West Africa

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Mike Wang
Research Roundup: UK vaccine center to help fight epidemics, global map of HIV reveals vaccine challenges, and researchers create antibodies to test and treat Zika

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Patrick McKern
Research Roundup: Male birth control one step closer to reality, three-in-one HIV drug launched, and powdered polio vaccine brings new hope

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Gabe Bienczycki
As the global fight against malaria stalls, malaria vaccine development could be primed for breakout

While the global fight against malaria stalls, we are closer than ever to a world where malaria vaccines join the battle arsenal.

PATH
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PATH/Matthew Dakin
Research Roundup: Access to Medicines index released, clinical trial of injectable ARV, and Zika vaccine clears early trial

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Mike Wang
Research Roundup: New treatment for sleeping sickness, innovations to combat AMR, and Merck Ebola vaccine update

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Satvir Malhotra
Research Roundup: Chikungunya vaccine trial, Ebola vaccine technology, and Zika biomarkers could lead to prenatal diagnostic

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Satvir Malhotra
Research Roundup: Effective experimental Ebola treatments, once-monthly injection to suppress HIV, and malaria-detecting dogs

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Gabe Bienczycki
Research Roundup: Suppository drug cuts child malaria deaths, J&J touts latest immune response data for 'mosaic' HIV vaccine program, and game changer TB drug

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Flickr/macwagen
Play: TRICK or TREATment?

To enjoy a bit of fun and mischief this Halloween, we’ve created a new game, TRICK or TREATment, to test our readers’ knowledge of global health technologies.

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PATH/Dan Chang
Research Roundup: Tech to stop a pandemic, DNA vaccine against Ebola, and a unique way to attack malaria

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Wendy Stone
Research Roundup: Rotavirus vaccine receives WHO prequalification, mosquito repellent paint, and new health security partnership

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Mike Wang
Research Roundup: Pledges from the UN High-Level Meeting on TB, TB vaccine trial success, and gene editing mosquitoes

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Eric Becker
Research Roundup: Neutralizing Ebola, a prototype to fight the next pandemic, and Zika vaccine trial moves forward

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Wendy Stone
Research Roundup: Long-acting HIV drugs, a universal flu vaccine candidate, and a low-cost device in the fight against malaria

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Gabe Bienczycki
Research Roundup: Innovations in bednets, contraception, and Zika vaccination trials

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Wanted: Tools to fight murderous mozzies and their deadly diseases

For World Mosquito Day, GHTC is taking a moment to shine a spotlight on the ghastly gang of mosquito-borne diseases and the innovations we need to finish these frightening foes for good.

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PATH/Georgina Goodwin
Research Roundup: Ebola vaccinations in North Kivu, the role of biobanks in research, and a new Zika vaccine candidate

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Doune Porter
10 brilliant technological innovations to save moms and babies

For many mothers and babies around the world, the first 48 hours after birth are the most dangerous of their lives. For eight years, Saving Lives at Birth—spearheaded by USAID—has challenged problem solvers worldwide to create innovative solutions to make birth safer and save lives. Here are ten incredible innovations from this initiative:

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PATH/Patrick McKern
Research Roundup: Dangerous outbreaks, commercializing a low-cost biologics platform, and success against an infection that blinds

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Eric Becker
Research Roundup: An experimental Ebola vaccine, new viruses discovered, and Australian experiment wipes out disease-carrying mosquitoes

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Gabe Bienczycki
Research Roundup: Updates in vaccine research and development and understanding parasitic hookworms

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Patrick McKern
Research Roundup: New breakthroughs in HIV and TB-detection research and 17 brave volunteers

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Wendy Stone
Research Roundup: Discovering new antibiotics in soil and harnessing gene therapy to fight AIDS

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Gena Morgan
Research Roundup: Two malaria drugs power to limit transmission and the latest on chikungunya and cholera vaccines

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Satvir Malhotra
Research Roundup: Rotavirus vaccine prequalified and breakthroughs in understanding leprosy and a long-acting malaria medicine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Doune Porter
Research Roundup: A malaria-fighting toothpaste ingredient and new vaccine candidates for schistosomiasis and tuberculosis

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Carib Nelson
Research Roundup: Unlocking a malaria mystery, WHO prequalifies new typhoid vaccine, and the power of vitamin C

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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Celebrating ten years of GHTC & a decade of progress in global health innovation

As we close out our 10th anniversary year, we wanted to take a moment to reflect on our shared progress and celebrate the headlines and moments that shaped global health R&D over the past decade. Check out some of the highlights...

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PATH/Mike Wang
Research Roundup: A powerful single-dose Cholera vaccine, breakthrough in understanding the malaria parasite, and a rapid urine test for TB

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Rocky Prajapati
Research Roundup: Environmental threat of AMR, obstacles with the dengue vaccine, and an Army-developed Zika candidate

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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Photo courtesy Bill & Melinda Gates Foundation/Lou Linwei
Research Roundup: A mosquito deliverer, the "fake" medicine crisis, and a promising typhoid vaccine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week

GHTC
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PATH/Gabe Bienczycki
Research Roundup: Dangers of immune response to Zika, curbing HIV/AIDS severity, and a potential leishmaniasis vaccine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week

GHTC
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PATH/Gabe Bienczycki
Research Roundup: An old-fashioned malaria strategy, a polio funding crisis, and a global pledge to end TB

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Georgina Goodwin
Research Roundup: Discerning between Zika and dengue, hope for a GBS vaccine, and killer mosquitoes as mosquito control

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Heng Chivoan
Research Roundup: Wearable immunization trackers, a potential pneumonia vaccine, and a newly recommended typhoid vaccine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Rocky Prajapati
Research Roundup: The immunization edition

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Gabe Bienczycki
Research Roundup: Nanopatch technology, agriculture and antibiotics, and a first-time pledge

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Georgina Goodwin
Research Roundup: An effective Rotavirus vaccine, prioritizing pediatric TB diagnostics, and a powerful HIV antibody

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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GHTC/Taylor Capizola
Overheard at UNGA: Innovation paves path to universal health coverage

A busy week at the 72nd United Nations General Assembly winds to a close with key discussions surrounding the global economic returns of health R&D.

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PATH/WIll Boase
Research Roundup: A Zika vaccine priority, partnerships for better cures, and a nationwide polio vaccine drive

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Gabe Bienczycki
Research Roundup: Technology to save mothers, an all-inclusive vaccine, and malaria's relationship with carbohydrates

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Andrew Berends
Research Roundup: Zika vaccine dead ends, an Ebola data-sharing platform, and a low-cost newborn asphyxia treatment

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Aaron Joel Santos
Research Roundup: Hope for an old TB vaccine, delivery drones, and malaria diagnostics

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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Novartis
Research Roundup: A new anti-malarial, the promise of probiotics, and genetically-engineered TB

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Evelyn Hockstein
Research Roundup: Plants as vaccines, the African CDC, and herd immunity in Zika

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Mike Wang
Research Roundup: Next generation technologies for vector control, tracking Zika, and treating resistant TB

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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CDC/ Sue Partridge, CDC- Ft. Collins
Research Roundup: Global immunization, Zika diagnostics, and an HIV treatment milestone

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Satvir Malhotra
Research Roundup: Vaccines as a tool to cure and protect, and what went right in the DRC Ebola outbreak

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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Heng Chivoan
Research Roundup: Polio mutation troubles, a pandemic bond, and Kenya's launch of a generic HIV drug

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Claire Suni
Research Roundup: Venom, technology for smart vector control & animals as a human health threat

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Lesley Reed
Research Roundup: Dengue diagnostics, unlocking protein structures, and an antibiotic found in soil

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Monique Berlier
Ensuring resistance doesn’t take hold: The importance of taking on typhoid now

Typhoid may seem like a distant memory in industrialized countries, but for many low- and middle-income countries it continues to cause millions of illnesses and about 150,000 deaths per year. New tools are needed to combat this looming threat.

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PATH/Gabe Bienczycki
Research Roundup: Malaria and bone density, a fatal vaccine error, and a sponsored Chikungunya trial

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Doune Porter
Research Roundup: CRISPR concerns, using innovation to cure malaria, and MSF's TB trial

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Patrick McKern
Research Roundup: Underestimating Zika & Chagas and hopes for the Ebola vaccine in the DRC

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Rocky Prajapati
Research Roundup: Potential malaria and Ebola vaccines and the polio vaccine shortage

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Claire Suni
Research Roundup: Barriers to TB immunization, malaria's genetic diversity, and IPM's dapivirine ring

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Aaron Joel Santos
Research Roundup: Breaking down Zika and opportunities, challenges surrounding global immunization

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Aaron Joel Santos
5 ways science is transforming global health and saving lives

Science expands our understanding, makes the impossible possible, and helps us build the future we want for all people. Science drives the work of GHTC, so we wanted to take a step back to reflect on five ways science is transforming global health.

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CDC/James Gathany
Research Roundup: Bacteria-sniffing dogs, vaccines for epidemics, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Evelyn Hockstein
Research Roundup: A virus-killing mask, testing drugs on pregnant women, and DARPA’s global health portfolio

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Gabe Bienczycki
Research Roundup: Roadkill reveals new drugs, bracelet saves preemies, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Dunia Faulx
A year in review: The top stories in global health innovation that shaped 2016

As the year comes to an end, GHTC is reflecting on the top stories in global health innovation that made news 2016. 

GHTC
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Architect of the Capitol
Research Roundup: HIV drug resistance, the 21st Century Cures Act, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Aaron Joel Santos
Research Roundup: A Zika treatment, an HIV cure, and a MERS vaccine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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National Institute of Allergy and Infectious Diseases
Research Roundup: Long-lasting pills, HIV testing, and starving bacteria of iron

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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National Institute of Allergy and Infectious Diseases
Research Roundup: Treating drug-resistant infections, Ebola virus mutations, and Zika vaccine clinical trials

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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National Institute of Allergy and Infectious Diseases
Research Roundup: Cow antibodies, Zika’s impact on male fertility, and hepatitis C research

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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David Jacobs
Research Roundup: Pharmaceutical waste and superbugs, resistance to insecticides, and vaccines for crises

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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National Institute of Allergy and Infectious Diseases
Research Roundup: Flu vaccines, HIV in kids, and a cross-continental R&D partnership

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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TB Alliance
Research Roundup: Kid-friendly TB treatment, drug manufacturing on-the-go, diarrheal disease, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Robin Biellik
Research Roundup: Diagnostics to combat antimicrobial resistance, vaccines for pandemic threats, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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David Jacobs
Research Roundup: Antibiotics, Zika vaccine R&D, and Ebola and malaria co-infection

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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National Institute of Allergy and Infectious Diseases, National Institutes of Health
Research Roundup: Placenta-on-a-chip, nasal bacteria against MRSA, and an experimental yellow fever vaccine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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International Partnership for Microbicides
Research Roundup: The HIV/AIDS and STIs edition

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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National Institute of Allergy and Infectious Diseases
Research Roundup: Update on Zika R&D

In this regular feature on Breakthroughs, we highlight the most promising Zika virus vaccine, drug, and diagnostic candidates as well as vector control approaches. 

GHTC
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James Gathany
Research Roundup: Viral hepatitis, treatment for persistent Ebola, E. coli–based vaccines

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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Sanofi Pasteur / Patrick Boulen
Yellow fever: Status of research, development, and access to countermeasures against an emerging epidemic

GHTC breaks down the status of R&D for vaccines, drugs, and diagnostics against yellow fever.

GHTC
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Architect of the Capitol
Research Roundup: Priority Review Voucher legislation, Toxic Shock Syndrome vaccine, and repurposing existing drugs

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Gabe Bienczycki
Research Roundup: Schistosomiasis drug resistance, a nanotechnology vaccine platform, and adjusting doses to bolster the yellow fever vaccine supply

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Glenn Austin
Research Roundup: New insights into Zika virus, using silk to preserve blood samples, and a single dose oral cholera vaccine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Doune Porter
Research Roundup: Yellow fever vaccine availability, protective antibodies against HIV, and the impact of past dengue infection on Zika fever

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Lesley Reed
Incentives and innovative financing mechanisms matter in addressing market failures

When existing market forces alone fall short in ensuring availability of and access to lifesaving health tools, a range of interventions are needed to alter the market and ultimately change the behavior of its actors.

GHTC
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Take 1.5 minutes for 1.5 million lives

In this guest post, Dara Erck, vice president of External Affairs at Aeras, a global nonprofit biotechnology organization, highlights a new video launched on World TB Day to raise awareness of the urgent need for new tools to combat tuberculosis (TB).

Aeras
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Research Roundup: Vaccines for Rift Valley Fever, MERS, and Zika

A vaccine candidate against Rift Valley Fever appears to be safe and effective for livestock and has the potential for use in humans.

GHTC
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A vaccine is essential to conclusively end HIV/AIDS: New modeling data catalyzes conversations around the end of HIV/AIDS and a vaccine’s role in getting there

In this guest post Tom Harmon, senior policy analyst at the International AIDS Vaccine Initiative (IAVI), highlights a new analysis exploring the critical role of a vaccine in ending AIDS.

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New affordable oral cholera vaccine receives WHO prequalification

In January, GHTC member International Vaccine Institute (IVI) announced that a new oral cholera vaccine it developed in partnership with Korean biotech company EuBiologics, Co. Ltd.—Euvichol®—received prequalification from the World Health Organization (WHO), paving the way for the vaccine to be purchased by global procurement bodies like Gavi, the Vaccine Alliance and UNICEF.

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Research Roundup: an Ebola vaccine, stillbirths, and antimicrobial R&D

Gavi, the Vaccine Alliance, signed an advanced purchase commitment, pledging to spend US$5 million on an Ebola vaccine currently under development by pharmaceutical company Merck & Co.

GHTC
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Research Roundup: Vaccines for cholera and river blindness and an online platform for pooled procurement

Last week, an oral cholera vaccine received World Health Organization (WHO) prequalification, a process of regulatory review which paves the way for procurement by United Nations agencies and international organizations.

GHTC
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Welcoming the National Action Plan for Combating Multidrug-Resistant Tuberculosis: Important first steps, critical next steps

In this guest post, Dara Erck, vice president of external affairs at Aeras, discusses the new White House National Action Plan for Combating Multidrug-Resistant Tuberculosis and how it could accelerate research and development (R&D) of new technologies to combat multidrug-resistant TB (MDR-TB).

Aeras
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365 review: Top global health innovation news of 2015

As 2015 draws to a close, the Global Health Technologies Coalition is reflecting on the past year in global health innovation.

GHTC
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Research Roundup: Preterm birth indicators, African sleeping sickness treatment, and the world’s first dengue vaccine

Virginia Commonwealth University (VCU) received a grant from the Global Alliance to Prevent Prematurity and Stillbirth, a member of the GHTC, to study the human microbiome in search of biomarkers to predict preterm birth.

GHTC
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Research Roundup: Snakebites, TB and parasitic infections, and HIV/AIDS vaccine development

Snakebites, which Médecins Sans Frontières describes as “one of the world's most neglected public health emergencies,” kill 200,000 people each year.

GHTC
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CDC/National Institute of Allergy and Infectious Diseases
Research Roundup: an aerosol TB vaccine, a new coating for HIV/AIDS drugs, drug-resistant malaria, and more

Researchers at Tulane University successfully tested an experimental aerosol tuberculosis (TB) vaccine in monkeys, demonstrating that the candidate was more effective in protecting against infection than BCG—the only TB vaccine on the market.

GHTC
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The R&D agenda and how it addresses access to vaccines

In this guest post, Dr. Jayasree K. Iyer—Chief Scientific Officer at the Access to Medicine Foundation—writes about the findings from their newest study, which examines the current state of the vaccine pipeline and how large pharmaceutical companies are considering access to these products.

Access to Medicine Foundation
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CDC/Dr. Scott Smith
Research Roundup: an HIV/AIDS vaccine candidate, inflatable incubator for premature babies, and US government R&D

Dr. Robert Gallo co-discovered the HIV virus and subsequently led the development of the first HIV/AIDS blood test.

GHTC
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Research Roundup: genetic protection against malaria, the vaccine pipeline, and counterfeit drugs and the FDA

A new study conducted by the Malaria Genomic Epidemiology Network (MalariaGEN)—a community of researchers across malaria-endemic regions—reveals a formerly unknown genetic variations that make people less susceptible to malaria.

GHTC
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PATH/Aaron Joel Santos
Research Roundup: priority review vouchers, diagnosing drug resistance, and oral and universal flu vaccines

Pharmaceutical company AbbVie is paying United Therapeutics US$350 million for its priority review voucher (PRV)—which expedites the US Food and Drug Administration’s (FDA) review of a product by four months—and EP Vantage speculates on their motive.

GHTC
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Research Roundup: a rapid diagnostic for three hemorrhagic fevers, a MERS vaccine to be tested in humans, and advances in R&D for HIV treatments

A new paper-based diagnostic can test for Ebola, dengue, and yellow fever in just ten minutes without running water, electricity, lab equipment, or highly-trained personnel.

GHTC
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Research Roundup: combatting malaria with forensics, detecting counterfeit drugs out of a suitcase, and preventing the flu without a vaccine

Luminol has long been used to detect blood at crime scenes, as it glows bright blue when it comes into contact with the blood protein hemoglobin, however, new research suggests that it could be repurposed to fight malaria in humans.

GHTC
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The latest in MERS R&D: Do we have the tools needed to prevent the next outbreak?

Since its discovery in 2012, cases of Middle East Respiratory Syndrome (MERS)—a disease World Health Organization (WHO) Director-General Dr. Margaret Chan called “a threat to the entire world”— have been reported in 27 countries across four continents.

GHTC
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Research Roundup: 3D-printed drugs, R&D in emergency settings, a universal flu vaccine, and more

The US Food and Drug Administration (FDA) approved the first 3D-printed drug last week, paving the way for the technology to be used to customize medical care to individual patients.

GHTC
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Research Roundup: a Chagas vaccine, new pediatric clinical trial resources, the “Nursery of the Future,” and more

Sabin Vaccine Institute—a member of GHTC—and Texas Children’s Hospital Center for Vaccine Development received a US$1.8 million grant to expedite the research and development of the first therapeutic vaccine for Chagas disease, which is currently undergoing preclinical research by the same team.

GHTC
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Research Roundup: a dengue vaccine, a breakthrough HIV treatment, antimicrobial R&D, and more

Later this year, French pharmaceutical company Sanofi plans to launch a vaccine for dengue fever, the first on the market for an infection for which nearly half of the world’s population is at risk.

GHTC
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Research Roundup: an aerosol vaccine for Ebola, software to enable clinical trials, an antibody against dengue fever, and more

An experimental, aerosol vaccine completely prevented infection from Ebola in monkeys, and will be tested in human clinical trials shortly.

GHTC
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Research Roundup: bacteria-eating viruses, experimental HIV and flu vaccines, and pharmaceutical law

With the looming threat of a post-antibiotic era—in which minor infections are fatal due to growing drug resistance—world leaders are examining remedies for treating bacterial infections from the pre-antibiotic era.

GHTC
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Research Roundup: a new contraceptive option, China’s role in global health R&D, and vaccines for MERS and pneumonia

Last week, GHTC member PATH launched the Caya® contoured diaphragm in the United States, after developing and testing nearly 200 prototypes to ensure the product was safe, effective, and user friendly.

GHTC
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PATH/Nguyen Ba Quang
Research Roundup: Middle East Respiratory Syndrome R&D, G7 support for antimicrobial and neglected tropical disease R&D, patient safety and the 21st Century Cures Act, and the contraceptive pipeline

The zoonotic Middle East Respiratory Syndrome (MERS), which World Health Organization (WHO) Director-General Dr. Margaret Chan called “a threat to the entire world” has spread to South Korea. More than 100 cases and 10 deaths have been reported, making it the largest outbreak outside of the Arabian Peninsula.

GHTC
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Will Boase
Research Roundup: inclusion of women in clinical trials, the future of vaccines, and diagnostics for counterfeit medicines and parasitic worms

United States Representatives Jim Cooper (D-TN) and Cynthia Loomis (R-WO) introduced the Research for All Act last week which calls for the inclusion of more women in clinical trials for products submitted for US Food and Drug Administration (FDA) approval.

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Photo courtesy of the David and Lucile Packard Foundation.
Could climate change lead to chikungunya? Examining the link between climate change and health

Polar bears and penguins aren’t the only species threatened by climate change.

GHTC
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PATH/Lesley Reed
Research Roundup: Leadership shifts at USAID, new discoveries in tuberculosis research, an emerging model for nonprofit pharmaceutical companies, and more

The US Agency for International Development (USAID) announced last week that Ariel Pabos-Mendez, the assistant administrator for Global Health, will serve as the coordinator for Child and Maternal Survival.

GHTC
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PATH/Mike Wang
Research Roundup: The 21st Century Cures Act, US funding for antimicrobial resistance, vaccine development and funding, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Will Boase
Research Roundup: Clinical trial data sharing, vaccines to look forward to, and public-private partnerships for global health research and development

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Gabe Bienczycki
Research Roundup: MenAfriVac® prequalification, an innovative new antibiotic, Ebola vaccine trials, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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Ten global health advancements I’m thankful for this Thanksgiving

As global health advocates, our work often requires us to focus on unmet needs—such as the number of people worldwide who still die from preventable diseases each year, or the lack of adequate resources and investment to tackle these diseases.

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PATH/Heng Chivoan
Research Roundup: Intellectual property awards, FDA priorities, Australia R&D, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Satvir Malhotra
Research Roundup: R&D in the post-2015 agenda, TB vaccines, the Global Innovation Fund, intellectual property, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Dan Chang
Research Roundup: Funding global health R&D, the neglected disease pipeline, Ebola vaccines, FDA approvals, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Eric Becker
Research Roundup: New malaria drugs, chikungunya vaccines, Africa Leaders Summit, preterm births coalition, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Evelyn Hockstein
Research Roundup: Saving Lives at Birth, US-Africa Leaders Summit, possible Ebola vaccine, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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Investing in global health innovation=smart power

During the past year, leaders from the US Global Leadership Coalition (USGLC)—an advocacy organization promoting diplomacy and development—have traveled across America seeking out innovators and innovations that best demonstrate how strategic US investments in global development can enhance America’s foreign policy and security interests—an approach USGLC calls “smart power” diplomacy.

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PATH/Will Boase
Research Roundup: EDCTP Forum, Sayana® Press, a new dengue vaccine, the 21st Century Cures Initiative, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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How R&D is saving #momandbaby and helping children reach their #5thbday

Tomorrow US policymakers and global health advocates will come together to talk progress made on preventing maternal and child deaths.

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NIAID
Research Roundup: FY 2015 appropriations, the Human Vaccines Project, Global Development Lab legislation, new HIV treatments, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Aaron Joel Santos
Could mapping the “human immunome” lead to the next generation of vaccines?

The answer is yes according to a group of 35 leading scientists who have come together to explore new strategies to accelerate vaccine development for deadly diseases such as malaria, HIV, tuberculosis (TB), and cancer.

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PATH/Evelyn Hockstein
Research Roundup: What we’re reading this week

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Evelyn Hockstein
Research Roundup: What we’re reading this week

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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AVAC
Celebrating progress on World AIDS Vaccine Day

Yesterday, May 18, marked the observance of World AIDS Vaccine Day­­–an annual event to focus attention on the need for a vaccine to prevent HIV infection and AIDS.

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Path/Mike Wang
Research Roundup: What we’re reading this week

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PAHO
Celebrating 20 years of public health advancements: Sabin Vaccine Institute’s Scientific Symposium

In a fitting way to kick off World Immunization Week, several hundred people gathered Friday, April 25th to celebrate significant achievements in vaccinology over the past two decades and to examine solutions for overcoming remaining hurdles at the Sabin Vaccine Institute’s 20th Anniversary Scientific Symposium.

Sabin Vaccine Institute
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PATH/Richard Franco
Research Roundup: What we’re reading this week

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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TB free breathing in the mines of South Africa: New TB vaccines could transform mining across the region

In this guest post, Kari Stoever, vice president of External Affairs at Aeras, writes about how mine workers are disproportionately affected by tuberculosis (TB) and why there’s an urgent need for new tools against this deadly disease.

Aeras
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PATH/Will Boase
Research Roundup: What we’re reading this week

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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GHTC
For 2015, the call for innovation is loud and clear

“We cannot solve what we need to solve with existing interventions—we need science and technology,” said Gary Cohen, executive vice president at Becton, Dickinson and Company (BD), at an official side event at the 6th Session of the Opening Working Group on Sustainable Development Goals this week in New York City.

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Vaccinate against the brain drain

In this guest post, Elisabeth Wilhelm, senior media specialist at the International AIDS Vaccine Initiative (IAVI), writes about the need to invest in the next generation of researchers and scientists in sub-Saharan Africa.

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India’s new rotavirus vaccine—and the innovative partnership that made it happen

In this guest post, Dr. John Boslego, director of PATH’s Vaccine Development Global Program, writes about an innovative partnership between the United States and India to develop an oral vaccine against rotavirus diarrhea.

PATH
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Working to protect against the dangers of dengue

In this guest post, Dr. Claire Huang, a researcher with the Centers for Disease Control and Prevention’s (CDC) Division of Vector-Borne Diseases, describes a dengue vaccine candidate developed by her team.

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PATH/Patrick McKern
Research Roundup: What we’re reading this week

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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