From Breakthroughs Blog: NTDs

 
PATH/Doune Porter
President signs spending bill boosting funding for global health

On February 15, President Trump signed into law a bipartisan spending bill—averting another partial government shutdown and ensuring full-year funding for the government for the remainder of fiscal year 2019. The months-long saga ended with some great news for global health and research and development.

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PATH/Jennifer Fox
As America leads, other nations step up to fund R&D to combat neglected disease threats

The US government has long played an indispensable role in driving global health progress as the world’s leading funder of research and development (R&D) for new vaccines, treatments, and other tools to fight neglected diseases.

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Wanted: Tools to fight murderous mozzies and their deadly diseases

For World Mosquito Day, GHTC is taking a moment to shine a spotlight on the ghastly gang of mosquito-borne diseases and the innovations we need to finish these frightening foes for good.

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PATH/Gabe Bienczycki
Research Roundup: R&D to defeat MRSA, West Nile Virus, and malaria-carrying mosquitoes

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Gabe Bienczycki
Research Roundup: Updates in vaccine research and development and understanding parasitic hookworms

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Patrick McKern
Research Roundup: New breakthroughs in HIV and TB-detection research and 17 brave volunteers

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Patrick McKern
Research Roundup: New work in malaria and HIV diagnostics and a widespread immunization campaign in Brazil

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Satvir Malhotra
Research Roundup: Rotavirus vaccine prequalified and breakthroughs in understanding leprosy and a long-acting malaria medicine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Doune Porter
Research Roundup: A malaria-fighting toothpaste ingredient and new vaccine candidates for schistosomiasis and tuberculosis

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Georgina Goodwin
Research Roundup: Stem cells and TB, the research agenda to end malaria, and a monkey species role in ending AIDS

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Carib Nelson
Research Roundup: Unlocking a malaria mystery, WHO prequalifies new typhoid vaccine, and the power of vitamin C

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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Sanofi Pasteur / Patrick Boulen
A year in review: The global health innovation stories that shaped 2017

As the year comes to an end, GHTC is reflecting on the top stories in global health innovation that made news in 2017.

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Celebrating ten years of GHTC & a decade of progress in global health innovation

As we close out our 10th anniversary year, we wanted to take a moment to reflect on our shared progress and celebrate the headlines and moments that shaped global health R&D over the past decade. Check out some of the highlights...

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PATH/Mike Wang
Research Roundup: A powerful single-dose Cholera vaccine, breakthrough in understanding the malaria parasite, and a rapid urine test for TB

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Rocky Prajapati
Research Roundup: Environmental threat of AMR, obstacles with the dengue vaccine, and an Army-developed Zika candidate

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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Photo courtesy Bill & Melinda Gates Foundation/Lou Linwei
Research Roundup: A mosquito deliverer, the "fake" medicine crisis, and a promising typhoid vaccine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week

GHTC
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PATH/Gabe Bienczycki
Research Roundup: Dangers of immune response to Zika, curbing HIV/AIDS severity, and a potential leishmaniasis vaccine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week

GHTC
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PATH/Georgina Goodwin
Research Roundup: Discerning between Zika and dengue, hope for a GBS vaccine, and killer mosquitoes as mosquito control

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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Umit Kartoglu
Research Roundup: Forest loss and Ebola, antibody-caused dengue complications, and a mosquito-monitoring platform

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Gabe Bienczycki
Research Roundup: Malaria and bone density, a fatal vaccine error, and a sponsored Chikungunya trial

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Patrick McKern
Research Roundup: Underestimating Zika & Chagas and hopes for the Ebola vaccine in the DRC

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Doune Porter
Research Roundup: Progress in fighting NTDs and TB, Polio eradication setbacks, and the crisis surrounding Chagas

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Dunia Faulx
A year in review: The top stories in global health innovation that shaped 2016

As the year comes to an end, GHTC is reflecting on the top stories in global health innovation that made news 2016. 

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PATH/Dan Chang
Research Roundup: Rapid test for bacterial infections, one drug to treat three neglected diseases, and innovations to combat Zika

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Gabe Bienczycki
Research Roundup: Schistosomiasis drug resistance, a nanotechnology vaccine platform, and adjusting doses to bolster the yellow fever vaccine supply

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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GHTC/Marissa Chmiola
GHTC briefing highlights critical role of US government in advancing global health innovation in an increasingly globalized world

On Tuesday, GHTC launched our seventh annual policy report through a congressional briefing and panel discussion. The critical role played by the US government in catalyzing global health research and development was a recurring theme, as panelists discussed the interconnectedness of global and American health and emphasized the need for new health tools to protect against outbreaks and continue progress.

GHTC
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PATH/A. Golden
Research Roundup: an affordable hepatitis C regimen, rapid diagnostics for neglected diseases, and fighting Zika with tires and milk

GHTC member the Drugs for Neglected Diseases initiative will test an affordable hepatitis C regimen in Malaysia and Thailand, with a guarantee from generic drug manufacturer Pharco Pharmaceuticals that, if successful, the product will be priced at no more than US$294 for the entire regimen.

GHTC
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Research Roundup: Vaccines for cholera and river blindness and an online platform for pooled procurement

Last week, an oral cholera vaccine received World Health Organization (WHO) prequalification, a process of regulatory review which paves the way for procurement by United Nations agencies and international organizations.

GHTC
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365 review: Top global health innovation news of 2015

As 2015 draws to a close, the Global Health Technologies Coalition is reflecting on the past year in global health innovation.

GHTC
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Research Roundup: flesh-eating bacteria treatment, Hepatitis C in Egypt, and access to compounds for drug discovery

Global Health Now took an in-depth look at the flesh-eating fungus mycetoma—which enters the body through cuts, and can result in swollen, deformed limbs—in a three-part series on this Untold Global Health Story of 2015.

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Research Roundup: Preterm birth indicators, African sleeping sickness treatment, and the world’s first dengue vaccine

Virginia Commonwealth University (VCU) received a grant from the Global Alliance to Prevent Prematurity and Stillbirth, a member of the GHTC, to study the human microbiome in search of biomarkers to predict preterm birth.

GHTC
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Research Roundup: Snakebites, TB and parasitic infections, and HIV/AIDS vaccine development

Snakebites, which Médecins Sans Frontières describes as “one of the world's most neglected public health emergencies,” kill 200,000 people each year.

GHTC
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PATH/Eric Becker
Research Roundup: Targeting cattle to fight sleeping sickness, antibodies that protect against distantly related viruses, and more

A new study suggests that the use of anti-parasitic drugs and insecticides in cattle can reduce human cases of Trypanosomiasis (sleeping sickness) by as much as 90 percent.

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CDC/Prof Woodridge Foster, Prof. Frank H. Collins
Research Roundup: repurposing ivermectin to fight malaria, LED lights against dengue fever, rapid diagnostics to slow antimicrobial resistance, and more

Findings of a study presented at the American Society of Tropical Medicine and Hygiene Annual Meeting last week suggest that ivermectin—a drug long used to treat river blindness and elephantiasis—can combat malaria when used in mass drug administration programs.

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CDC/Dr. Scott Smith
Research Roundup: an HIV/AIDS vaccine candidate, inflatable incubator for premature babies, and US government R&D

Dr. Robert Gallo co-discovered the HIV virus and subsequently led the development of the first HIV/AIDS blood test.

GHTC
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CDC
Research Roundup: TB R&D, malaria in pregnancy, and treatments for filarial diseases

A new briefing paper from the Infectious Diseases Society of America Center for Global Health Policy explores the state of tuberculosis (TB) research and development (R&D) including challenges for products currently in the pipeline and gaps in TB research.

GHTC
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Why we need research to detect, prevent, and ultimately, eliminate parasitic diseases

In this guest post, Dr. Monica Parise—deputy director for program and science—and Dr. Larry Slutsker—director of the Division of Parasitic Disease and Malaria—at the US Centers for Disease Control and Prevention (CDC) Center for Global Health—discuss the role of research in advancing efforts to detect, prevent, and eliminate parasitic diseases.

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PATH/James Gathaney
Research Roundup: antibiotic and reproductive health R&D, leadership at the FDA, and a potential new strain of dengue fever.

The US Department of Health and Human Services (HHS) announced last week a partnership with pharmaceutical company AstraZeneca for the research and development (R&D) of antibiotics.

GHTC
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Research Roundup: HIV/AIDS self-testing and advances in dengue fever and sleeping sickness R&D

A new study suggests that with basic training, individuals can learn to accurately and safely test themselves for HIV/AIDS.

GHTC
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PATH/Aaron Joel Santos
Research Roundup: priority review vouchers, diagnosing drug resistance, and oral and universal flu vaccines

Pharmaceutical company AbbVie is paying United Therapeutics US$350 million for its priority review voucher (PRV)—which expedites the US Food and Drug Administration’s (FDA) review of a product by four months—and EP Vantage speculates on their motive.

GHTC
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Research Roundup: a rapid diagnostic for three hemorrhagic fevers, a MERS vaccine to be tested in humans, and advances in R&D for HIV treatments

A new paper-based diagnostic can test for Ebola, dengue, and yellow fever in just ten minutes without running water, electricity, lab equipment, or highly-trained personnel.

GHTC
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Research Roundup: 3D-printed drugs, R&D in emergency settings, a universal flu vaccine, and more

The US Food and Drug Administration (FDA) approved the first 3D-printed drug last week, paving the way for the technology to be used to customize medical care to individual patients.

GHTC
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Research Roundup: a Chagas vaccine, new pediatric clinical trial resources, the “Nursery of the Future,” and more

Sabin Vaccine Institute—a member of GHTC—and Texas Children’s Hospital Center for Vaccine Development received a US$1.8 million grant to expedite the research and development of the first therapeutic vaccine for Chagas disease, which is currently undergoing preclinical research by the same team.

GHTC
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Research Roundup: a dengue vaccine, a breakthrough HIV treatment, antimicrobial R&D, and more

Later this year, French pharmaceutical company Sanofi plans to launch a vaccine for dengue fever, the first on the market for an infection for which nearly half of the world’s population is at risk.

GHTC
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Research Roundup: an aerosol vaccine for Ebola, software to enable clinical trials, an antibody against dengue fever, and more

An experimental, aerosol vaccine completely prevented infection from Ebola in monkeys, and will be tested in human clinical trials shortly.

GHTC
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PATH/Gabe Bienczycki
How to accelerate innovation to solve the world's most urgent health issues

In this post, Amie Batson, MBA—chief strategy officer at GHTC member PATH—discusses a new PATH-led initiative to identify and showcase lifesaving innovations with the promise to transform global health by 2030 and offers insights into what it will take to accelerate the impact of innovation. This post originally appeared in the Innovation Countdown 2030 Report: Reimagining Global Health.

PATH
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PATH/Christopher Nelson
Research Roundup: a promising antimalarial and leishmaniasis vaccine, diagnostics for tuberculosis, and more

The Medicines for Malaria Venture (MMV)—a member of the GHTC—and the University of Dundee’s Drug Discovery Unit have developed an antimalarial compound that could treat drug-resistant cases of malaria with a single dose.

GHTC
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Research Roundup: cross-sector partnerships to advance drug discovery, global recommendations for contraceptive use, and a diagnostic that detects lifetime viral exposure

The Drugs for Neglected Diseases initiative (DNDi)—a member of the GHTC—is partnering with pharmaceutical companies Eisai Co., Shionogi & Co., Takeda Pharmaceutical, and AstraZeneca to accelerate early-stage research for drugs against Chagas and leishmaniasis.

GHTC
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World Health Assembly roundup: News on global health research and innovation

The 68th World Health Assembly (WHA) in Geneva wrapped up last week after addressing several items that will shape the next few years of global health innovation.

GHTC
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Research Roundup: priority review voucher sells for record price, WHO action to address antimicrobial resistance, and more

The French pharmaceutical company Sanofi purchased a priority review voucher (PRV)—which entitles the owner to an expedited review of a future product by the US Food and Drug Administration (FDA)—for US$245 million last week.

GHTC
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CDC
Research Roundup: clinical trials for experimental Ebola vaccines, genetic traits that affect malaria risk, and progress toward a hookworm vaccine

The National Institute of Allergy and Infectious Diseases (NIAID) announced last week that two experimental Ebola vaccines appear to be safe for widespread use, based on early results of clinical trials in Liberia.

GHTC
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PATH/Heng Chivoan
Research Roundup: A new drug for tuberculosis, contraceptive research and development, drug-resistant malaria, and more

The TB Alliance, a member of the Global Health Technologies Coalition, announced last week that it will be starting Phase 1 clinical trials for a new tuberculosis (TB) drug candidate.

GHTC
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DNDi/João Roberto Ripper
Chagas disease: A silent kiss and a neglected killer

Valentine’s Day seems like a fitting occasion to shine some needed light on a disease that can begin with a late-night “kiss” but ends with a broken heart.

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PATH/Wendy Stone
Research Roundup: FDA Commissioner to step down, a Grand Challenge for neglected diseases, funding for reproductive health research and development, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Will Boase
Research Roundup: Clinical trial data sharing, vaccines to look forward to, and public-private partnerships for global health research and development

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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Ten global health advancements I’m thankful for this Thanksgiving

As global health advocates, our work often requires us to focus on unmet needs—such as the number of people worldwide who still die from preventable diseases each year, or the lack of adequate resources and investment to tackle these diseases.

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Why invest in R&D for HIV, TB and malaria? Because it’s good for global health, and good for Europe

In this post, Eoghan Walsh—communications officer at Deutsche Stiftung Weltbevoelkerung (DSW)—writes about the need for Europe to increase financial and political support for efforts aimed at creating new ways to tackle diseases such as HIV/AIDS, tuberculosis (TB) and malaria.

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Research Roundup: Appropriations, Ebola, AIDS 2014, open working groups, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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Senate shows strong support for global health R&D in defense appropriations bill and report

Earlier this month, we reported that both the House and Senate Appropriations Committees included language supporting global health research and development (R&D) in their reports concerning funding for the Department of State, foreign operations and related programs.

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PATH/Will Boase
Research Roundup: EDCTP Forum, Sayana® Press, a new dengue vaccine, the 21st Century Cures Initiative, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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European and African countries meet to advance health technology development for poverty-related diseases

Earlier this week, Anne Hradský—advocacy coordinator for Global Health Research and Development (R&D), Katharina Scheffler—advocacy officer—and others from Deutsche Stiftung Weltbevoelkerung (DSW)—joined other European and African stakeholders for the Seventh European & Developing Countries Clinical Trials Partnerships (EDCTP) Forum in Berlin, Germany.

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PATH/Robin Biellik
Research Roundup: SFOPS, new FDA guidance, top trends in global health, new report on global health R&D, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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House and Senate support global health R&D in appropriations reports

While lawmakers battled it out on the field last week during the annual Congressional Baseball Game (Democrats won for the sixth year in a row!), they found something they could join together on as the House Appropriations Committee easily approved the State and Foreign Operations Subcommittee’s (SFOPS) appropriations bill on Tuesday afternoon.

GHTC
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International Partnership for Microbicides
Research Roundup: Microbicides, hookworm vaccines, #MomAndBaby, pediatric HIV treatments, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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NIAID
Research Roundup: FY 2015 appropriations, the Human Vaccines Project, Global Development Lab legislation, new HIV treatments, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Eric Becker
Research Roundup: New drugs against diarrhea, the End Neglected Tropical Diseases Act, genetically-modified mosquitoes, and mines

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PATH/Evelyn Hockstein
Research Roundup: What we’re reading this week

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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EDCTP2: What it means for European support for global health R&D

In this guest post, Renate Baehr—executive director of Deutsche Stiftung Weltbevoelkerung—writes about the next rendition of the European & Developing Countries Clinical Trials Partnership (EDCTP) and how its expansion will impact more lives in low- and middle-income countries.

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Path/Mike Wang
Research Roundup: What we’re reading this week

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Aaron Joel Santos
Research Roundup: What we’re reading this week

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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PAHO
Celebrating 20 years of public health advancements: Sabin Vaccine Institute’s Scientific Symposium

In a fitting way to kick off World Immunization Week, several hundred people gathered Friday, April 25th to celebrate significant achievements in vaccinology over the past two decades and to examine solutions for overcoming remaining hurdles at the Sabin Vaccine Institute’s 20th Anniversary Scientific Symposium.

Sabin Vaccine Institute
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PATH/Matthew Dakin
Research Roundup: What we’re reading this week

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

GHTC
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The human face of global health R&D: Brian D’Cruz and USAID

The US Agency for International Development (USAID) is the nation’s lead foreign assistance agency.

GHTC
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Three key research developments you might have missed from the ASTMH Annual Meeting

In this guest post, Jaclyn Schiff—American Society of Tropical Medicine and Hygiene (ASTMH) Director of Communications—highlights news in global health research presented during the recent ASTMH Annual Meeting.

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New fact sheet outlines the global health R&D pipeline and why US support is so important

In the past, the United States has contributed to important breakthroughs in global health—from the eradication of smallpox to a 74 percent drop in measles deaths worldwide.

GHTC
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