R&D Resource Library

AIDS Vaccine Advocacy Coalition (AVAC)
HIV Prevention Research & Development Investments, 2017: Investing to end the epidemic

In its 14th annual report, the Resource Tracking for HIV Prevention Research & Development Working Group documents research and development spending for the calendar year 2017 and analyzes funding trends spanning seventeen years.

PDF

Report

HIV/AIDS

Funding

US

Treatment Action Group
2018 Pipeline Report

An annual review of therapeutics, diagnostics, vaccines, and preventive technologies in development for HIV, hepatitis C virus (HCV), and tuberculosis, along with immune-based and gene therapies and research toward a cure for HIV.

Read More

Report

HIV/AIDS

TB

Policy Analysis

State of Research & Development

Multilateralism for GHTC: Overview brief

Provides an overview of the opportunities and institutions GHTC targets in the multilateral arena, why GHTC advocates in that arena, and how our members and partners can participate in these opportunities.

PDF

Fact Sheet

Report

Global Health Crosscutting

Multilateral

Policy Analysis

Enhancing GHSA’s role in supporting global health R&D to advance health security

Provides background on the Global Health Security Agenda (GHSA) and limitations with its current structure, and offers recommendations to expand the comprehensiveness of the program in advancing global health security through the adoption of a new action package on global health R&D.

PDF

Fact Sheet

Antimicrobial Drug Resistance

Emerging Infectious Diseases

Policy Analysis

R&D Capacity Strengthening

Multilateral

Return On Innovation: Learn how global health R&D delivers for your state

Interactive online tool and individualized state fact sheets documenting how US investments in global health R&D are delivering economic and health benefits across American states.

View

Fact Sheet

Website

Global Health Crosscutting

Economic Impact

Funding

US

GHTC
Bolstering BARDA’s role in combatting naturally occurring threats and emerging infectious diseases

Provides background on the mission of the Biomedical Advanced Research and Development Authority (BARDA), its engagement to date in combatting naturally occurring threats and emerging infectious diseases, and limitations that hinder its ability to sustain and increase activities in this space.

PDF

Fact Sheet

Antimicrobial Drug Resistance

Emerging Infectious Diseases

Policy Analysis

US

GHTC
Pandemic and All-Hazards Preparedness Reauthorization Act priorities

Recommends actions to bolster BARDA’s role in developing medical countermeasures against naturally occurring threats and emerging infectious diseases through the 2018 reauthorization of the Pandemic and All-Hazards Preparedness Act.

PDF

Fact Sheet

Antimicrobial Drug Resistance

Emerging Infectious Diseases

Policy Analysis

US

NIH
NIAID TB Portals Program

The NIAID TB Portals Program is a multi-national collaboration for tuberculosis (TB) data sharing and analysis to advance TB research.

Learn More

Antimicrobial Drug Resistance

Health Impact Data

TB

Website

Policy Cures Research
G-Finder 2017: Neglected Disease Research and Development: Reflecting on a Decade of Global Investment

Annual report providing the most comprehensive analysis of public, private, and philanthropic investment in R&D for neglected diseases. 

PDF

Report

Global Health Crosscutting

HIV/AIDS

Malaria

NTDs

TB

Funding

State of Research & Development

US

Treatment Action Group
The Ascent Begins: Tuberculosis Research Funding Trends, 2005–2016

Analyzes trends in tuberculosis R&D funding from 2005 through 2016.

PDF

Report

TB

Funding

Policy Analysis

State of Research & Development

US

PATH/Therese Bjorn Mason
Innovating Foreign Assistance: Harnessing the Power of the Private Sector to Achieve US Global Health and Development Goals

Identifies challenges to forging effective partnerships across sectors and offers recommended policy changes to fully leverage the comparative advantages of each sector to advance US global health and development goals.

PDF

Report

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Policy Analysis

US

PATH/DSW
Going Further Together–The Case for European Union partnership with Africa on Regulatory Harmonization

Provides practical recommendations for how policymakers in the European Union (EU) can strengthen support and accelerate progress of regulatory harmonization in Africa. The report also lays out the status of harmonization efforts underway across Africa, how they are being supported by the EU and opportunities for increased partnership.

PDF

Report

Global Health Crosscutting

Access

Case studies

Policy Analysis

R&D Capacity Strengthening

Regulatory

SDGs

Healthier World, Safer America: A US Government Roadmap for International Action to Prevent the Next Pandemic

Provides analysis of the importance of developing a robust pipeline of new drugs, diagnostics, vaccines, and other technologies for diseases likely to become pandemics, and outlines recommendations for action from the US government to prevent the next pandemic.

PDF

Report

Antimicrobial Drug Resistance

Emerging Infectious Diseases

Economic Impact

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

R&D Capacity Strengthening

US

HIV Prevention Research & Development Investments 2000–2016: Investment priorities to fund innovation in a challenging global health landscape

Annual report tracking and analyzing global investment in biomedical HIV/AIDS prevention R&D for the calendar year 2016 and analyzes funding trends spanning 16 years.

PDF

Report

HIV/AIDS

Funding

US

Shigemi Nakamura-Simms, Pokadot Graphic (Australia)
Return on innovation: Why global health R&D is a smart investment for the United States

Examines the impact of US government investment in global health R&D at home and abroad, from delivering lifesaving tools for the world’s most vulnerable people to generating economic and security returns for the United States.

Learn More

Report

Global Health Crosscutting

Case studies

Economic Impact

Health Impact Data

Funding

State of Research & Development

US

CDC/NCEZID
Emerging and Zoonotic Infectious Diseases

Profiles the work of the National Center for Emerging and Zoonotic Infectious Diseases at the US Centers for Disease Control and Prevention.

PDF

Report

Antimicrobial Drug Resistance

Emerging Infectious Diseases

NTDs

Case studies

US

PATH/Gabe Bienczycki
Accelerating US Progress in Combating Malaria Worldwide: Recommendations for Maximizing Investments Toward a World Free From Malaria

Provides recommendations for the US Administration and Congress to accelerate progress toward a malaria-free world. 

PDF

Report

Malaria

Economic Impact

Funding

Policy Analysis

US

Committee on Global Health and the Future of the United States; Board on Global Health; Health and Medicine Division; National Academies of Sciences, Engineering, and Medicine
Global Health and the Future Role of the United States

Assesses the current global health landscape and how challenges, actions, and players have evolved over the last decade across a wide range of issues, and provides recommendations for US policymakers on how to increase responsiveness, coordination, and efficiency–both within the US government and across the global health field.

PDF

Report

Global Health Crosscutting

Case studies

Economic Impact

Funding

Incentives & Innovative Financing

Policy Analysis

R&D Capacity Strengthening

Regulatory

US

Access to Medicine Foundation
2017 Access to Vaccines Index

Provides the first landscape of industry activity to improve immunization coverage and assesses vaccine companies based on their efforts to improve access to vaccines in low- and middle-income countries.

PDF

Report

Global Health Crosscutting

Access

Case studies

R&D Capacity Strengthening

State of Research & Development

Policy Cures Research
G-FINDER 2016: Neglected Disease Research and Development: A Pivotal Moment for Global Health

Annual report providing the most comprehensive analysis of public, private, and philanthropic investment in R&D for neglected diseases. The 2016 report also tracks investment in R&D for Ebola and other African viral hemorrhagic fevers.

View

Report

Emerging Infectious Diseases

Global Health Crosscutting

HIV/AIDS

Malaria

NTDs

TB

Funding

State of Research & Development

US

Duke Margolis Center for Health Policy, Duke Global Health Institute, The Center for Policy Impact in Global Health, Policy Cures Research
Strengthening the US Government's Role in Product Development for Global Health

Provides an overview of US government entities engaged in global health product development, the funding landscape, and how funding decisions are determined.

PDF

Report

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Policy Analysis

Regulatory

US

Advocacy Coalition for Health Research and Development
Navigating the Research Approval and Regulatory Landscape for Health Technologies in Kenya

Provides an overview of regulatory processes and bodies in Kenya and challenges and causes of regulatory delays, as well as provides recommendations to policymakers to strengthen the regulatory environment in Kenya.

PDF

Fact Sheet

Global Health Crosscutting

Policy Analysis

Regulatory

SEEK Development
Donor Tracker

Online resource that offers free, independent, up-to-date analysis of 14 major development assistance donor nations. Provides data-driven insights on strategic priorities, funding trends, decision-making and key opportunities in a number of topical areas including global health R&D.

View

Website

Global Health Crosscutting

Funding

Policy Analysis

TB Alliance
Voices of TB

Library featuring videos about tuberculosis (TB). Covers a range of subjects including TB R&D, market access, drug-resistence, and patient stories.

View

Video

TB

Case studies

International AIDS Vaccine Initiative
HIV/AIDS Vaccine Impact Modeling

Interactive tool allowing users to explore the impact of a future potential preventive HIV/AIDS vaccine, used in conjunction with existing HIV-prevention tools, in different scenarios of coverage and efficacy. Covers five regions including Southern Africa, Eastern Africa, Asia, Latin America, and Eastern Europe.

View

Website

HIV/AIDS

Health Impact Data

HarvestPlus
Biofortification: The Nutrition Revolution Is Now

Provides background information on the problem of micronutrient deficiency. Explains what biofortification is and the role it can play in addressing this challenge.

View

Website

Nutrition

State of Research & Development

BioVentures for Global Health
Global Health Primer

Provides compiled and synthesized information on drugs, vaccines, and diagnostics in use or in development for the management of 25 different neglected diseases.

View

Website

Global Health Crosscutting

State of Research & Development

Kaiser Family Foundation
U.S. Global Health Budget Tracker

Provides regularly updated information on US government appropriations for global health as well as historic trends. Can be refined by agency, program, health area, and initiative. Not specific to global health R&D, but rather covers all US government investment in global health.

View

Website

Global Health Crosscutting

Funding

US

US National Institutes of Health
World RePORT

Interative tool tracking biomedical research projects funded by US government agencies worldwide, as well as research funded by other large organizations.

View

Website

Global Health Crosscutting

Funding

US

World Health Organization
WHO Global Health R&D Observatory

Online database from the World Health Organization that provides a centralized and comprehensive source of data on what health R&D is being conducted globally, where it is being conducted, by whom and how, and to facilitate the development of standards for data collection and analysis in this area. Currently in beta form.

View

Website

Global Health Crosscutting

Funding

Multilateral

State of Research & Development

AVAC
HIV Prevention Research & Development Database

Comprehensive database of information on biomedical HIV/AIDS prevention clinical trials that are planned, ongoing, or completed. Provides summary information and the ability to filter search by select criteria.

View

Website

HIV/AIDS

State of Research & Development

Policy Cures, Deutsche Stiftung Weltbevolkerung
Saving Lives: Making the case for European investment in poverty-related and neglected disease R&D

Analyzes European public funding for R&D for poverty-related and neglected diseases from 2007–2014, assessing trends, impact, and return on investment.

PDF

Report

Global Health Crosscutting

Case studies

Economic Impact

Funding

Health Impact Data

Policy Analysis

R&D Capacity Strengthening

State of Research & Development

Policy Cures
G-FINDER Public Search Tool

Public search tool providing open access to G-FINDER survey data which includes comprehensive data on public, private sector, and philanthropic investment in R&D for neglected diseases. Data is available from financial years 2007 and beyond.

View

Website

Global Health Crosscutting

Funding

Access to Medicine Foundation
Access to Medicines Index 2016

Biennial report that independently assesses and ranks the world’s 20 largest pharmaceutical companies based on their efforts to improve access to medicine in low- and middle-income countries.

PDF

Report

Global Health Crosscutting

Access

R&D Capacity Strengthening

State of Research & Development

Infectious Diseases Society of America
Zika: From obscurity, to emergency, to enduring public health threat

Provides background on the Zika outbreak and global response, and provides recommendations for future action.

PDF

Fact Sheet

Emerging Infectious Diseases

Funding

Policy Analysis

State of Research & Development

US

International Partnership for Microbicides
Why Microbicides for Women?

Explains why women urgently need female-initiated tools they can use to protect themselves against HIV/AIDS and explains how microbicides are an important part of the broader HIV/AIDS prevention toolkit.

PDF

Fact Sheet

HIV/AIDS

Sexual & Reproductive Health

Funding

State of Research & Development

The Lancet Commission on Essential Medicines Policies
Essential medicines for universal health coverage

Analyzes lessons learned in fostering access to essential medicines and offers recommendations to expand access to medicines and other health technologies.

PDF

Report

Global Health Crosscutting

Access

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

R&D Capacity Strengthening

Regulatory

SDGs

Alive & Thrive, PATH
Brief: Establishing the First Human Milk Bank in Viet Nam

This brief details the establishment and anticipated impact of Vietnam's first human milk bank, which will improve access to donor human breastmilk for between 3,000 and 4,000 at-risk infants annually.

View PDF

Fact Sheet

Maternal/Newborn/Child health

HIV Vaccines & Microbicides Resource Tracking Working Group
HIV Prevention Research & Development Funding Trends, 2000–2015

Annual report tracking and analyzing global investment in biomedical HIV/AIDS prevention R&D.

PDF

Report

HIV/AIDS

Funding

US

Treatment Action Group
2016 Report on Tuberculosis Research Funding Trends, 2005–2015: No Time To Lose

Analyzes trends in tuberculosis R&D funding from 2005 through 2015.

PDF

Report

TB

Funding

Policy Analysis

State of Research & Development

US

HarvestPlus
Biofortified Staple Food Crops: Who is Growing What?

This map illustrates the more than 50 countries that have adopted biofortified crops and the specific crops that are available and/or being tested in each country.

View PDF

Graphic

Nutrition

World Health Organization
Target Regimen Profiles for TB Treatment

This report outlines target product profiles for tuberculosis treatment regimens to guide the drug development process towards important regimen characteristics corresponding to the needs of end-users.

View PDF

Report

TB

Multilateral

AVAC
HIV Vaccines: An Introductory Factsheet

Provides background information about R&D for an HIV/AIDS vaccine and key developments in the field.

View

Fact Sheet

HIV/AIDS

State of Research & Development

Infectious Diseases Society of America
Global antimicrobial resistance

Provides background on the growth of antimicrobial resistance and global response, and provides recommendations for future action

PDF

Fact Sheet

Antimicrobial Drug Resistance

Economic Impact

Policy Analysis

State of Research & Development

US

Infectious Diseases Society of America
Ebola

Provides background on the Ebola outbreak and global response, and provides recommendations for future action.

PDF

Fact Sheet

Emerging Infectious Diseases

Funding

Policy Analysis

State of Research & Development

US

PATH
Harnessing the power of innovation to save mothers and children: How 11 emerging innovations could save more than 6 million lives

Explores how 11 emerging innovations for women, newborns, and children could help dramatically accelerate progress in maternal and child survival, specifically in the context of USAID’s 24 priority countries. The 11 innovations we modeled were identified through the Innovation Countdown 2030 initiative.

PDF

Report

Maternal/Newborn/Child health

Sexual & Reproductive Health

Case studies

Health Impact Data

US

AVAC
Microbicides for HIV Prevention: An Introductory Factsheet

Provides background information on how microbicides work and the current state of R&D for microbicide products.

View

Fact Sheet

HIV/AIDS

State of Research & Development

AVAC
HIV Cure Research: An Introductory Factsheet

Provides background information on the field of HIV/AIDS cure research, the scientific evidence to date, and key R&D strategies currently being pursued.

Fact Sheet

HIV/AIDS

State of Research & Development

AVAC
Multipurpose Prevention Technologies (MPTs): An Introductory Factsheet

Provides background information on what multipurpose prevention technologies are and the current state of R&D for these products.

View

Fact Sheet

HIV/AIDS

Sexual & Reproductive Health

State of Research & Development

United Nations Secretary-General's High-Level Panel on Access to Medicines
Report of the United Nations Secretary-General's High-Level Panel on Access to Medicines: Promoting innovation and access to health technologies

Report from an independent panel, convened by the United Nations Secretary-General, to explore the twin challenges of innovation and access to medicines. Offers recommendations in the areas of intellectual property and access to health technologies; new incentives for health R&D; and governence, accountability, and transparency.

PDF

Report

Global Health Crosscutting

Access

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

R&D Capacity Strengthening

SDGs

Infectious Diseases Society of America
AIDS 2016: Progress and Challenge

Examines developments and challenges in HIV/AIDS and tuberculosis research, treatment, prevention, and funding presented at the 21st International AIDS Conference.

PDF

Fact Sheet

HIV/AIDS

TB

Health Impact Data

State of Research & Development

Making Innovation Matter: Conference Report From The Innovation Effect

Conference report from The Innovation Effect: Powering Disruptive Global Health Solutions event convened on June 15, 2016, which brought together more than 150 leading global health and development thinkers in Washington, DC to discuss leveraging partnership, disruptive technologies, systems, and data driven insights to create dramatic improvements in the health and well-being of people around the world.

PDF

Report

Global Health Crosscutting

US

AVAC
ARV-Based Prevention Pipeline

Illustrates the pipeline of antiretroviral (ARV)-based HIV/AIDS prevention products under development, including oral pills, vaginal rings, vaginal and rectal gels, vaginal films, and long-acting injectable ARVs.

View

Fact Sheet

Graphic

HIV/AIDS

State of Research & Development

PATH/Lesley Reed
Medicines Regulation in the East African Community: Landscape Summary Report

Provides an overview of current regulatory systems within the East African Community and within partner states, as well as summarizes key challenges and other findings and identifies potential solutions that could be the focus of future policy advocacy efforts.

PDF

Fact Sheet

Report

Policy Analysis

Regulatory

R&D Capacity Strengthening

PATH
The Journey of Innovation: Advocacy at Every Step

Explores the role of advocacy in advancing innovative solutions to improve the health and well-being of people around the world.

View

Case studies

US

AVAC
Microbicides by the Numbers: Science, products, money and more

Provides an overview of key facts about microbicide R&D, including clinical trials underway and current levels of global investment in microbicide R&D.

View

Fact Sheet

Graphic

HIV/AIDS

Funding

State of Research & Development

Treatment Action Group
2016 Pipeline Report: HIV & TB

Annual report examining new developments in drugs, diagnostics, vaccines, preventive technologies, cure research, and immune-based and gene therapies for HIV/AIDS and tuberculosis (TB).

PDF

Report

HIV/AIDS

TB

Policy Analysis

State of Research & Development

The 69th World Health Assembly: Background and outcomes

Provides background on World Health Assembly (WHA) operations and analysis of policy outcomes from the 69th WHA which will impact global health R&D.

Learn More

Report

Antimicrobial Drug Resistance

Global Health Crosscutting

Access

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

US Agency for International Development
2015 USAID Health-Related Research and Development Progress Report

Annual report providing an update on the US Agency for International Development’s (USAID) activities and progress in health R&D. Includes appendix itemizing the agency’s expenditures of funds for health R&D.

PDF

Report

Global Health Crosscutting

Funding

US

Treatment Action Group
Breathing Life into Flatlined U.S. Government Funding for Tuberculosis Research: FY 2017–2020 Allocations and Recommendations

Provides an overview of investments made by the US government in tuberculosis (TB) R&D and explains how increasing funding can catalyze the development of better vaccines, diagnostics, and treatments for TB.

PDF

Fact Sheet

TB

Funding

Policy Analysis

US

International Partnership for Microbicides
Microbicide Overview

Provides background information on the potential impact of microbicides for HIV/AIDS prevention and an overview of microbicide products in late-stage clinical development.

PDF

Fact Sheet

HIV/AIDS

Sexual & Reproductive Health

State of Research & Development

PATH/Evelyn Hockstein
Global health R&D: What's at stake during the 69th WHA?

Webinar exploring health R&D issues on the agenda at the 69th World Health Assembly (WHA).

Learn More

Video

Antimicrobial Drug Resistance

Global Health Crosscutting

Access

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

SDGs

US National Institutes of Health
Global Health Matters Newsletter

E-newsletter, distributed every two months from the US National Institutes of Health Fogarty International Center, providing the latest information on global health research.

View

Website

Global Health Crosscutting

State of Research & Development

US

Research and development at the 69th World Health Assembly

Provides background and analysis on the agenda items under discussion at the 69th World Health Assembly which could impact global health R&D.

PDF

Fact Sheet

Antimicrobial Drug Resistance

Global Health Crosscutting

Access

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

SDGs

Médecins Sans Frontières
Lives on the Edge: Time to Align Medical Research and Development with People’s Health Needs

Examines the gap in availability of effective, affordable technologies to address the health needs of people in low- and middle-income countries and analyzes a broad range of policies aimed at changing this dynamic by incentivizing R&D of accessible medical tools that respond to patient needs.

PDF

Report

Global Health Crosscutting

Access

Case studies

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

Infectious Diseases Society of America
Tuberculosis

Provides background on the tuberculosis epidemic and global response, and provides recommendations for future action.

PDF

Fact Sheet

TB

Funding

Policy Analysis

State of Research & Development

US

Infectious Diseases Society of America
HIV

Provides background on the HIV/AIDS epidemic and global response, and provides recommendations for future action.

PDF

Fact Sheet

HIV/AIDS

Funding

Policy Analysis

State of Research & Development

US

AVAC
AIDS Vaccines by the Numbers: Trials, discoveries, money and more

Provides an overview of key facts about HIV/AIDS vaccine R&D, including the number of vaccine trials underway and current levels of global investment in HIV/AIDS vaccine R&D.

View

Fact Sheet

Graphic

HIV/AIDS

Funding

State of Research & Development

International Partnership for Microbicides
New Technologies for Women's HIV Prevention: The Payoff for Sustainable Development

Explains why R&D to meet women’s sexual and reproductive health needs is a smart investment that will accelerate progress in meeting the Sustainable Development Goals.

PDF

Report

HIV/AIDS

Sexual & Reproductive Health

Health Impact Data

Multilateral

SDGs

State of Research & Development

US Department of Health and Human Services
The Global Strategy of the U.S. Department of Health and Human Services

Outlines the global strategy of the US Department of Health and Human Services.

PDF

Government Policy

Global Health Crosscutting

R&D Capacity Strengthening

US

Council on Foreign Relations
Back to the Future of Global Health Security

Outlines necessary elements of a comprehensive approach to emerging infectious diseases.

View

Fact Sheet

Emerging Infectious Diseases

Funding

Incentives & Innovative Financing

Policy Analysis

Briefing: Achieving a bold vision for global health: Policy solutions to advance global health R&D

Video of congressional briefing held on April 19, 2016 to launch GHTC's seventh annual policy report. Panelists included: Dr. Peter Hotez, President, Sabin Vaccine Institute; Dean, National School of Tropical Medicine, Baylor College of Medicine; Science Envoy, US Department of State; Dr. Patrick Kachur, Principal Deputy Director, Center for Global Health, US Centers for Disease Control and Prevention; Ambassador Jimmy Kolker, Assistant Secretary for Global Affairs, US Department of Health and Human Services; and Dr. David Shoultz, Global Program Leader, Drug Development and Devices and Tools, PATH. The event was moderated by Erin Will Morton, Director of GHTC.

View

Video

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Policy Analysis

US

Achieving a bold vision for global health: Policy solutions to advance global health R&D

Seventh annual GHTC policy report outlining actions US government can take to support strong global health R&D investment, improve coordination, and strengthen regulatory pathways to ultimately accelerate development of urgently-needed health tools.

Learn More

Fact Sheet

Report

Global Health Crosscutting

Case studies

Funding

Incentives & Innovative Financing

Multilateral

R&D Capacity Strengthening

Regulatory

SDGs

US

PATH, NEPAD
Increasing access to high-quality, safe health technologies across Africa: African Union Model Law on Medical Products Regulation

Examines challenges in regulatory capacity and harmonization in African nations and analyzes the African Union Model Law on Medical Products Regulation, which is intended to help increase harmonization and collaboration across nations.

PDF

Fact Sheet

Global Health Crosscutting

Access

Multilateral

R&D Capacity Strengthening

Regulatory

Review on Antimicrobial Resistance
Vaccines and Alternative Approaches: Reducing our Dependence on Antimicrobials

In-depth technical report on vaccines and innovative approaches to reducing antibiotic use to address antimicrobial resistance.

PDF

Report

Antimicrobial Drug Resistance

Funding

Incentives & Innovative Financing

Health Impact Data

Multilateral

Policy Analysis

State of Research & Development

HarvestPlus
Biofortification Evidence Brief

Summarizes the latest evidence on efficacy and impact of biofortified crops to address micronutrient deficiency.

PDF

Fact Sheet

Report

Nutrition

Economic Impact

Health Impact Data

State of Research & Development

US Food and Drug Administration
FDA Drug Approval Process Infographic

Illustrates the drug approval process at the US Food and Drug Administration (FDA).

PDF

Fact Sheet

Graphic

Global Health Crosscutting

Regulatory

US

Policy Cures
The Birth Lottery: Changing the Odds

Details the need for increased global investment in R&D for reproductive health technologies, illustrates why such investment is a best buy, and highlights promising innovations in development for maternal and newborn health.

PDF

Fact Sheet

Maternal/Newborn/Child health

Sexual & Reproductive Health

Case studies

Economic Impact

Health Impact Data

Better together? Exploring the proposal for a pooled fund for global health research and development

Webinar discussing the World Health Organization’s (WHO) Global Health R&D Observatory, coordination mechanisms, and proposals to create a pooled fund to support health R&D for diseases relevant to low- and middle-income countries

Learn More

Video

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

Why is health R&D critical to achieving the SDGs?

Video exploring why R&D for new health technologies is key to tackling the world’s most pressing health issues. It is the first installment in a four-part series asking experts to reflect on the role of global health innovation in achieving the Sustainable Development Goals (SDGs).

View

Video

Global Health Crosscutting

Multilateral

SDGs

What can we do to accelerate health innovation to reach SDGs?

Video asking experts how health R&D can be accelerated. It is the second installment in a four-part series on the role of global health innovation in achieving the Sustainable Development Goals (SDGs).

View

Video

Global Health Crosscutting

Funding

Multilateral

SDGs

What innovations have the greatest potential to transform global health?

Video asking experts to reflect on which next-generation health technologies they believe will drive dramatic change in global health. It is the third installment in a four-part series on the role of global health innovation in achieving the Sustainable Development Goals.

View

Video

Global Health Crosscutting

Multilateral

SDGs

State of Research & Development

Why does global health innovation matter to you personally?

Video asking experts why they care personally about health R&D. It is the fourth installment in a four-part series on the role of global health innovation in achieving the Sustainable Development Goals.

View

Video

Global Health Crosscutting

Case studies

Multilateral

SDGs

BioVentures for Global Health
Global Health Primer

Provides compiled and synthesized information on drugs, vaccines, and diagnostics in use or in development for the management of 25 different neglected diseases.

View

Website

Global Health Crosscutting

State of Research & Development

PATH
Research and Development for Health in South Africa: Landscape analysis executive summary

Landscape analysis exploring the governance structures and policies shaping South Africa’s funding for and engagement in health R&D. Includes policy recommendations to strengthen health R&D in South Africa.

PDF

Fact Sheet

Global Health Crosscutting

Funding

Policy Analysis

R&D Capacity Strengthening

Regulatory

PATH
Research and Development for Health in Kenya: Landscape analysis executive summary

Landscape analysis exploring the governance structures and policies shaping Kenya’s investment and engagement in health R&D. Includes policy recommendations to strengthen health R&D in Kenya.

PDF

Fact Sheet

Global Health Crosscutting

Funding

Policy Analysis

R&D Capacity Strengthening

International AIDS Vaccine Initiative
Research and Development of New Biomedical HIV Prevention Tools for Women and Girls

Provides background information on the need for new and improved R&D prevention tools designed specifically for women and girls, as well as recommendations to better align HIV/AIDS prevention R&D with the needs of women and girls in sub-Saharan Africa.

PDF

Fact Sheet

Report

HIV/AIDS

White House
White House National Action Plan for Combating Multidrug-Resistant Tuberculosis

Outlines the US government cross-agency strategy to combat multidrug-resistant tuberculosis.

PDF

Government Policy

TB

Antimicrobial Drug Resistance

Economic Impact

R&D Capacity Strengthening

US

Policy Cures Research
Neglected Disease Product Pipeline [website]

Interactive website providing the most up-to-date overview of the current state of the product development pipeline for neglected diseases. The Policy Cures Research pipeline provides results by disease and technology type.

 

View

Website

TB

HIV/AIDS

Global Health Crosscutting

Malaria

State of Research & Development

NTDs

Pipeline

Policy Cures
G-FINDER 2015 Neglected Disease Research and Development: The Ebola Effect

Annual report providing the most comprehensive analysis of public, private, and philanthropic investment in R&D for neglected diseases. The 2015 report was expanded to track R&D funding for Ebola-related products.

PDF

Report

Emerging Infectious Diseases

Global Health Crosscutting

HIV/AIDS

Malaria

NTDs

TB

Funding

State of Research & Development

US

amfAR, IAVI, Johns Hopkins Bloomberg School of Public Health, UNDP
Respect, Protect, and Fulfill

This guidance informs collaboration between researchers and community-based organizations around studies of HIV treatment and prevention interventions involving gay men and other men who have sex with men.

View PDF

Report

HIV/AIDS

World Health Organization
A global action framework for TB research in support of the third pillar of WHO’s end TB strategy.

This Framework was developed by the World Health Organization to foster high-quality tuberculosis research over the subsequent 10 years (2016-2025) at global and national levels.

View PDF

Government Policy

Report

TB

Multilateral

Treatment Action Group
HIV Cure Research Fact Sheet

Provides background on HIV/AIDS cure research, current approaches, and progress.

PDF

Fact Sheet

HIV/AIDS

State of Research & Development

Global Health Council
Mapping the Road to Better Health

Visually maps the transition of the health-related Millennium Development Goals to the Sustainable Development Goals.

PDF

Fact Sheet

Graphic

Global Health Crosscutting

Multilateral

SDGs

International Partnership for Microbicides
Microbicides for Women’s HIV Prevention

Explains what microbicides are, how they work, and what current research is underway to develop microbicide-based HIV/AIDS prevention products.

View

Video

HIV/AIDS

Sexual & Reproductive Health

State of Research & Development

Review on Antimicrobial Resistance
Rapid Diagnostics: Stopping the Unnecessary Use of Antibiotics

In-depth technical report on the importance of existing and new diagnostics in addressing antimicrobial resistance.

PDF

Report

Antimicrobial Drug Resistance

Funding

Incentives & Innovative Financing

Policy Analysis

State of Research & Development

Policy Cures
The Unrecognised Revolution in Global Health [fact sheet]

Provides an overview of the current state of the product development pipeline for neglected diseases.

PDF

Fact Sheet

Global Health Crosscutting

State of Research & Development

Chatham House
Rethinking the Global Health System

Assesses priority areas for reform as the global health architecture transitions into the post-2015 era, including looking at ways to expand R&D financing. Maps global health actors, emerging trends, and reform proposals, as well as providing recommendations to improve the global health system.

PDF

Report

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

SDGs

PATH, US Agency for International Development, Norwegian Agency for Development Cooperation, Bill & Melinda Gates Foundation
Innovation Countdown 2030: Reimagining Global Health [fact sheet]

Summarizes finding and technologies in Innovation Countdown 2030, a report which profiles 30 lifesaving innovations with the greatest potential to accelerate progress to reach the health targets in the Sustainable Development Goals.

PDF

Fact Sheet

Global Health Crosscutting

State of Research & Development

A pipeline of promise: Global health research and product development process

Infographic illustrating the R&D process for global health technologies and the challenges faced in advancing products through the R&D pipeline.

PDF

Fact Sheet

Graphic

Global Health Crosscutting

Access

Regulatory

Global health R&D dictionary

Dictionary with definitions of frequently-used terms in the global health R&D field.

Learn More

Website

Global Health Crosscutting

Infectious Diseases Society of America, HIV Medicine Association
Right Now: Observations on an HIV treatment pivot in Mozambique

In this report on the Global Center's fifth congressional study tour to Africa, the Global Center gives a firsthand account of the HIV treatment scale-up in Mozambique through programming from the US President's Emergency Plan for AIDS Relief.

PDF

Report

HIV/AIDS

Case studies

Policy Analysis

US

Infectious Diseases Society of America
Redeployment: Opportunities to Control HIV and TB in Tanzania—Observations from Dar es Salaam, Mbeya and Zanzibar

In this report on the Global Center's congressional study tour to Tanzania, the Center discusses how US funding is used to combat the HIV/AIDS and tuberculosis epidemics in one of the hardest hit countries in sub-Saharan Africa.

PDF

Report

HIV/AIDS

TB

Case studies

Policy Analysis

R&D Capacity Strengthening

US

Infectious Diseases Society of America
Tuberculosis Research and Development: A quest for tools to meet the 21st century challenges of an ancient disease

Examines the diagnostic, treatment, and prevention needs for addressing tuberculosis (TB), the state of R&D for these interventions, and US government engagement in TB R&D.

PDF

Report

TB

Case studies

Funding

Policy Analysis

State of Research & Development

US

GHTC
US government programs involved in global health R&D: Website list

Lists the major US government programs involved in global health R&D and their corresponding website URLs.

PDF

Fact Sheet

Website

Global Health Crosscutting

US

Measuring global health R&D for the post-2015 development agenda

Calls for the United Nations and its Member States to acknowledge the importance of global health R&D in the Sustainable Development Goals (SDGs) and include robust indicators to measure progress toward this purpose in the SDG monitoring framework, recommending the most suitable indicators.

Learn More

Report

Global Health Crosscutting

Multilateral

Policy Analysis

SDGs

Turning ambition into action: The critical role of health innovation in achieving the Sustainable Development Goals

Provides an overview of the content and global health R&D indicators recommended in the report Measuring global health R&D for the post-2015 development agenda, which was commissioned by the Council on Health Research for Development, GHTC, the International AIDS Vaccine Initiative, Medicines for Malaria Venture, PATH, and the TB Alliance.

PDF

Fact Sheet

Global Health Crosscutting

Policy Analysis

Multilateral

SDGs

Health innovation and the Sustainable Development Goals

Provides background on the Sustainable Development Goals (SDGs), the critical role of health innovation in achieving the goals, and actions the US government can take to support health R&D to meet the SDGs.

PDF

Fact Sheet

Global Health Crosscutting

Multilateral

Policy Analysis

US

PATH
Diabetes Supplies: Are they there when needed?

This report aims to raise awareness of the availability and affordability of essential medicines and technologies for diabetes in low-resource settings, and inspire a broad range of stakeholders at the global and national levels to take concerted action to address this issue.

View PDF

Report

Access

PATH, US Agency for International Development, Norwegian Agency for Development Cooperation, Bill & Melinda Gates Foundation
Innovation Countdown 2030: Reimagining Global Health [report]

Profiles 30 lifesaving innovations with the greatest potential to accelerate progress to reach the health targets in the Sustainable Development Goals. The innovations were identified through a crowdsourcing process and evaluation by a panel of independent health experts. Includes health impact modeling for a subsection of innovations featured.

PDF

Report

Global Health Crosscutting

Case studies

Economic Impact

Health Impact Data

State of Research & Development

Policy Cures
The Role of "Team India" in Global Health R&D

Examines the role of the Indian government and pharmaceutical industry in global health R&D. It looks at funding trends, as well as policies, programs, and partnerships in India that advance R&D.

PDF

Report

Global Health Crosscutting

Economic Impact

Funding

Policy Analysis

State of Research & Development

Trade and access to medicines analysis

One-page analysis on trade, intellectual property rights, and access to medicines.

PDF

Fact Sheet

Global Health Crosscutting

Access

US

FHI 360
Calliope, the Contraceptive Pipeline Database

Calliope, the Contraceptive Pipeline Database, provides information on new and future contraceptive products, including long-acting and novel products currently only available in limited markets.

View

Website

Sexual & Reproductive Health

State of Research & Development

FHI 360
Contraceptive Technology Innovation Exchange

The Contraceptive Technology Innovation (CTI) Exchange offers resources about contraceptive research and development, including information about products currently in development, preclinical and clinical research, and opportunities for future investment. This easily searchable resource library also includes information about regulatory requirements, quality assurance standards, intellectual property, and product introduction strategies, as well as tools for advocacy.

View

Website

Sexual & Reproductive Health

Regulatory

State of Research & Development

Kaiser Family Foundation
The U.S. Government Engagement in Global Health: A Primer

Provides background information on the breadth of US government support for global health, landscaping analysis of the agencies and programs engaged in this work and policies governing this activity, and an overview of major topical US priorities in global health. Not specific to global health R&D, rather covers the breadth of US government global health activities.

PDF

Report

Global Health Crosscutting

Funding

Multilateral

US

Achieving access to new innovations: Perspectives on the challenges & opportunities of global health R&D

Webinar discussing the challenges that hinder the development of and access to new global health technologies and the different approaches being taken in the R&D process to overcome these challenges and achieve widespread access.

Learn More

Video

Global Health Crosscutting

Access

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

The FDA's role in global health: Helping safe, effective health tools reach people in need worldwide

Outlines the US Food and Drug Administration's (FDA) role in global health R&D and offers recommendations for how the FDA can continue to strenghten its engagement.

PDF

Fact Sheet

Global Health Crosscutting

Policy Analysis

Regulatory

US

Saving lives through research: USAID's role in creating breakthrough global health products

Explains the critical role of the US Agency for International Development (USAID) in global health R&D.

PDF

Fact Sheet

Global Health Crosscutting

Policy Analysis

US

New products hold the key to health improvement worldwide

Outlines the important contributions that the US government has made to global health R&D and why it is critical that the United States continue to support the global health research pipeline.

PDF

Fact Sheet

Global Health Crosscutting

Funding

Policy Analysis

State of Research & Development

US

PATH
Investing in Vaccines for the Developing World

Examines the challenges in developing and delivering vaccines for neglected global diseases and looks at innovative funding mechanisms to finance vaccine R&D and delivery.

PDF

Fact Sheet

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Multilateral

PATH
The Road to Safe and Effective Vaccines: Clinical Trials and Their Role in Providing Lifesaving Vaccines

Explains what clinical trials are, how they work, and the role they play in ensuring that vaccines introduced to the market are safe and effective.

PDF

Report

Global Health Crosscutting

Regulatory

PATH
A History of Vaccines

Looks at the history and impact of vaccines, providing an overview of disease rates both before and after vaccine introduction.

PDF

Fact Sheet

Global Health Crosscutting

Health Impact Data

State of Research & Development

International Partnership for Microbicides
Why a Diverse Pipeline for HIV Prevention?

Explains why a diverse product pipeline of tools to reduce the risk of HIV infection is critical to continuing HIV/AIDS prevention progress. Provides background on currently available HIV/AIDS prevention options and new technologies under development.

PDF

Fact Sheet

HIV/AIDS

Sexual & Reproductive Health

State of Research & Development

Health innovation in the post-2015 agenda: Looking ahead

Webinar discussing the debate and next steps in defining the Sustainable Development Goals (SDGs), targets, and indicators and the role of health innovation in the success of the SDGs and their impact on global health.

Learn More

Video

Global Health Crosscutting

Multilateral

Policy Analysis

SDGs

Meeting the challenge, seizing the opportunity: US leadership can advance global health R&D

Sixth annual GHTC policy report outlining actions the United States can take to help reduce deaths, extend lives, and secure healthier futures by supporting R&D for new health tools.

Learn More

Fact Sheet

Report

Global Health Crosscutting

Economic Impact

Health Impact Data

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

Regulatory

US

SEEK Development, Policy Cures, EACH Coalition
Assessing EU Funding for R&D for Poverty-Related and Neglected Diseases

Analyzes European Union (EU) strategy, programmatic support, and financing for R&D for poverty-related and neglected diseases and antimicrobial resistance. Provides policy recommendations to enhance the impact of EU support.

PDF

Report

Global Health Crosscutting

Access

Funding

Incentives & Innovative Financing

Policy Analysis

R&D Capacity Strengthening

Regulatory

Global Health Council
Taking Stock: Why U.S. Investments in Global Health Matter

Briefing book designed for members of the 114th US Congress and staff to provide background and recommendations on US government involvement in global health. It includes a section on health R&D.

PDF

Report

Global Health Crosscutting

Case studies

Economic Impact

Funding

Policy Analysis

US

Global Panel on Agriculture and Food Systems for Nutrition
Biofortification: An Agricultural Investment for Nutrition

This policy brief lays out technical evidence and arguments for expanding support for biofortification as an element of nutrition-sensitive national agricultural research and investment strategies. It recommends that policymakers implement biofortification as one of several complementary approaches to reduce micronutrient deficiencies.

View PDF

Fact Sheet

Nutrition

Policy Analysis

Policy Cures
G-FINDER 2014 Reproductive Health: R&D for the Developing World

Provides comprehensive analysis of public, private, and philanthropic investment in R&D for reproductive health products targeting the needs of low- and middle-income countries.

PDF

Report

Sexual & Reproductive Health

Case studies

Funding

State of Research & Development

US

Global Alliance to Prevent Prematurity and Stillbirth
Preterm Birth & Stillbirth: The Challenge

This fact sheet provides an overview of the global burden and impact of preterm birth and stillbirth and innovative solutions to address these challenges.

View PDF

Fact Sheet

Maternal/Newborn/Child health

Aeras
Exposed

Four-part video series examining the deadly global tuberculosis (TB) epidemic and the race to develop new prevention tools, including new TB vaccines.

View

Video

TB

Case studies

Policy Cures
Australia’s Global Health R&D Investment: Achieving its Potential

Analyzes Australia’s investment and engagement in neglected disease R&D and provides recommendations to enhance that impact.

PDF

Fact Sheet

Global Health Crosscutting

Funding

Policy Analysis

Pooling resources to advance global health R&D

Webinar discussing pooled funding mechanisms as a resource to support and advance global health R&D.

Learn More

Video

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

US Food and Drug Administration
The FDA's Drug Review Process: Ensuring Drugs Are Safe and Effective

Explains the drug approval process at the US Food and Drug Administration (FDA).

Website

Global Health Crosscutting

Regulatory

US

From idea to impact: How the US government can improve coordination of global health research and development

Provides an overview of current US government agency programming in global health R&D, highlights areas of success and areas for improvment, and provides recommendations to improve strategic alignment and coordination of US-supported global health R&D activities.

Learn More

Report

Global Health Crosscutting

Case studies

Policy Analysis

US

How the US government can improve coordination for global health R&D

Outlines the need for greater interagency coordination among US government agencies and programs engaged in global health R&D and provides a set of recommendations for achieving this goal.

PDF

Fact Sheet

Global Health Crosscutting

Case studies

Policy Analysis

US

Global Alliance to Prevent Prematurity and Stillbirth
Every Preemie — SCALE

This fact sheet details the Every Preemie—SCALE (Scaling, Catalyzing, Advocating, Learning, and Evidence-Driven) project, which aims to catalyze global uptake of interventions for preterm and low birthweight infants, overcome obstacles to the delivery of interventions and services, and increase coverage and utilization of perinatal care services.

View PDF

Fact Sheet

Maternal/Newborn/Child health

Washington Global Health Alliance
Washington State Global Health Landscape Study

Landscape study examining the global health industry (including health R&D actors) in Washington State. It uses new and existing data to measure and quantify the economic significance of the global health industry to Washington, including employment figures and fiscal impacts.

PDF

Report

Global Health Crosscutting

Economic Impact

Funding

US

The role of research and innovation in the post-2015 development agenda: Bridging the divide between the richest and the poorest within a generation

Builds a case for why R&D for new and improved health technologies targeting the needs of low- and middle-income countries should be a critical component of the post-2015 development agenda.

Learn More

Report

Global Health Crosscutting

Case studies

Economic Impact

Funding

Health Impact Data

Multilateral

Policy Analysis

SDGs

Policy Cures
Tuberculosis: The Last Mile

Examines the limitations of current approaches to controlling tuberculosis (TB), analyzes global investment in TB R&D, and provides an overview of TB products in the product development pipeline.

PDF

Report

TB

Case studies

Funding

Health Impact Data

State of Research & Development

Deutsche Stiftung Weltbevoelkerung
EDCTP 2 In a Nutshell

Provides background information on the European & Developing Countries Clinical Trial Partnership (EDCTP)—a European Union program that supports clinical trials and regulatory system strengthening in low- and middle-income countries.

PDF

Fact Sheet

Global Health Crosscutting

Funding

Incentives & Innovative Financing

R&D Capacity Strengthening

Regulatory

GHTC, DSW, Policy Cures
2015 and beyond: The role of innovation for health in a new development framework

Explores the importance of health R&D to achieving development objectives and offers recommendations from GHTC, DSW, and Policy Cures on how the United Nations can ensure innovation is included in the post-2015 agenda.

PDF

Report

Global Health Crosscutting

Access

Funding

Multilateral

Policy Analysis

R&D Capacity Strengthening

SDGs

Summary paper: Advancing research and development to address poverty-related and neglected diseases and conditions

Summary of findings from a briefing paper series examining nonprofit product developer (NPPD) perspectives on financing and coordination of health R&D. It provides an overview of the key challenges, lessons, and potential solutions identified by NPPDs in their efforts to advance the development of health technologies for low- and middle-income countries.

Learn More

Report

Global Health Crosscutting

Access

Funding

Incentives & Innovative Financing

Policy Analysis

R&D Capacity Strengthening

Regulatory

Innovation for a changing world: The role of US leadership in global health R&D

Fifth annual GHTC policy report providing recommendations that Congress and the Administration can use to leverage the United States' important role in global health R&D.

Learn More

Fact Sheet

Report

Global Health Crosscutting

Economic Impact

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

Regulatory

SDGs

US

Briefing paper, Volume 5: Working with partners to strengthen local research and manufacturing capacity

Outlines efforts by nonprofit product developers to strengthen the research and manufacturing capacity of academic, nongovernmental, and commercial partners in low- and middle-income countries. It is the fifth volume in a briefing series on financing and coordination of health R&D.

Learn More

Report

Global Health Crosscutting

Access

Case studies

Policy Analysis

R&D Capacity Strengthening

World Health Organization
High-priority target product profiles for new tuberculosis diagnostics

This meeting report details target product profiles for tuberculosis diagnostics to align the needs of end-users with the specifications and targets that product developers.

View PDF

Report

TB

Multilateral

Briefing Paper, Volume 4: Addressing regulatory challenges throughout the product development proces

Outlines the most significant regulatory challenges faced by nonprofit product developers and partners throughout the product development process and describes how these challenges affect their work. It is the fourth volume in a briefing series on financing and coordination of health R&D.

Learn More

Report

Global Health Crosscutting

Access

Case studies

Multilateral

Policy Analysis

R&D Capacity Strengthening

Regulatory

Drugs for Neglected Diseases initiative
An Innovative Approach to R&D for Neglected Patients: Ten Years of Experience and Lessons Learned by DNDi

Explores lessons learned by the Drugs for Neglected Disease initiative (DNDi) from a decade of conducting R&D for health technologies to address neglected diseases.

PDF

Report

Global Health Crosscutting

Access

Case studies

Funding

Incentives & Innovative Financing

Policy Analysis

R&D Capacity Strengthening

Regulatory

State of Research & Development

Policy Cures, Deutsche Stiftung Welbevoelkerung
European Innovation & PRNDs

Provides background information on the burden of poverty-related and neglected diseases (PRNDs) and examines European Union investment and policies supporting R&D of health technologies to address PRNDS.

PDF

Fact Sheet

Graphic

Global Health Crosscutting

Economic Impact

Funding

Lancet Commission on Investing in Health
Global health 2035: a world converging within a generation

Examines the global case for investment in health, including R&D, and the current resource gap. Based on economic and health impact modeling, it lays out an investment roadmap for the world to achieve dramatic health gains by 2035.

PDF

Report

Global Health Crosscutting

Economic Impact

Funding

Health Impact Data

Incentives & Innovative Financing

Multilateral

State of Research & Development

Policy Cures
An Emerging Leader: Germany’s Role in Neglected and Poverty-Related Disease R&D

Examines the role of Germany in neglected disease R&D and looks at trends in German funding from 2007–2012.

PDF

Report

Global Health Crosscutting

Economic Impact

Funding

Health Impact Data

Policy Analysis

Policy Cures, Medicines for Malaria Ventures, FIND, Innovative Vector Control Consortium, PATH
From Pipeline to Product: Malaria R&D Funding Needs

Tool to guide policymakers’ investment in new health technologies to control malaria and move toward the goal of eradication. It looks at what is in the malaria product pipeline, where funding is on track or falling behind, and the estimated funding needed for R&D of new malaria tools until 2022.

PDF

Report

Malaria

Case studies

Funding

Health Impact Data

Policy Analysis

State of Research & Development

Briefing paper, Volume 3: Improving the affordability, availability, and acceptability of health technologies

Describes how nonprofit product developers and their partners try to ensure access in low- and middle-income countries to the knowledge and technologies they develop. It is the third volume in a briefing series on financing and coordination of health R&D.

Learn More

Report

Global Health Crosscutting

Access

Policy Analysis

R&D Capacity Strengthening

Regulatory

Briefing Paper, Volume 2: Financing health research and development

Provides the perspectives of nonprofit product developers on the most significant funding challenges and the types of financing mechanisms that support their work. It is the second volume in a briefing series on financing and coordination of health R&D.

Learn More

Report

Global Health Crosscutting

Access

Case studies

Funding

Incentives & Innovative Financing

Policy Analysis

Improving health at home and abroad

Examines how the US Food and Drug Administration (FDA) can maximize its investment and global impact. This brief offers actionable recommendations that the FDA can implement to strengthen the United States’ legacy in global health.

PDF

Fact Sheet

Global Health Crosscutting

Policy Analysis

Regulatory

US

Accelerating Health Research for Africa’s Development

Analyzes the involvement of eastern and southern African nations in health R&D and the national policies and government entities shaping that engagement. Provides policy recommendations to strengthen African-led health R&D and innovation.

PDF

Fact Sheet

Report

Global Health Crosscutting

Economic Impact

Funding

Policy Analysis

R&D Capacity Strengthening

Briefing paper, Volume 1: Developing technologies to address poverty-related and neglected diseases and conditions

Explores how nonprofit product developers approach product development and describes the key challenges they and their partners face in developing and introducing technologies that address the health needs of low- and middle-income countries. It is the first volume in a briefing series on financing and coordination of health R&D.

Learn More

Report

Global Health Crosscutting

Access

Case studies

Funding

Policy Analysis

R&D Capacity Strengthening

Regulatory

PATH
Public-private partnerships for global health: How PATH advances technologies through cross-sector collaboration

Provides background on the role of public-private partnerships in global health R&D and provides case studies on how PATH has worked in partnership with other sectors to advance health technology development.

PDF

Fact Sheet

Report

Global Health Crosscutting

Case studies

Funding

Incentives & Innovative Financing

Policy Analysis

Renewing US leadership: Policies to advance global health research

Fourth annual GHTC policy report offering actionable recommendations that Congress and the Administration can implement to strengthen the US legacy in global health R&D and, more importantly, save lives around the world.

Learn More

Fact Sheet

Report

Global Health Crosscutting

Economic Impact

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

Regulatory

US

US Agency for International Development
USAID Health-Related Research and Development Strategy, 2011-2015

Outlines the health R&D strategy of the US Agency for International Development (USAID) for 2011 through 2015.

PDF

Government Policy

Global Health Crosscutting

Funding

US

Milken Institute
Innovative Financing for Global Health R&D

Examines innovative financing tools and mechanisms that could be used to mobilize increased funding for global health R&D.

PDF

Report

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Policy Analysis

Kaiser Family Foundation
The US Department of Defense & Global Health

Analyzes the US Department of Defense’s role in global health, examining its organizational structure, activities, strategy, policy, and budget for activities in global health.

PDF

Report

Global Health Crosscutting

Funding

Policy Analysis

US

Policy Cures, Deutsche Stiftung Weltbevoelkerung
Saving Lives and Creating Impact: EU investment in poverty-related and neglected diseases

Analyzes European Union (EU) (both European Commission and member states) engagement and investment in R&D for poverty-related and neglected diseases from 2007–2010, assessing trends, impact, and return on investment.

PDF

Report

Global Health Crosscutting

Case studies

Economic Impact

Funding

Health Impact Data

Policy Analysis

R&D Capacity Strengthening

State of Research & Development

March of Dimes, World Health Organization, The Partnership for Maternal, Newborn, and Child Health, Save the Children
Born Too Soon: The Global Action Report on Preterm Birth

Highlights the first-ever national, regional, and global estimates of preterm birth incidences, examines current and future health interventions to address preterm birth, and lays out priorities for action, including further R&D.

PDF

Report

Maternal/Newborn/Child health

Sexual & Reproductive Health

Case studies

Health Impact Data

Policy Analysis

Bill & Melinda Gates Foundation, DSW, GHTC, Policy Cures
Creating the tools of tomorrow: Investing in global health R&D

Examines advances in global health tools over the last few years, as well as the need for new and innovative partnerships, and increased investment in global health R&D. Created by the Bill & Melinda Gates Foundation, DSW, GHTC, and Policy Cures.

PDF

Fact Sheet

Report

Global Health Crosscutting

Case studies

Funding

Health Impact Data

Policy Analysis

Institute of Medicine of the National Academies
Ensuring Safe Foods and Medical Products Through Stronger Regulatory Systems Abroad

Assesses the challenges in regulating food and health products globally and provides recommendations for the US Food and Drug Administration to implement to strengthen regulatory systems in low- and middle-income countries.

PDF

Report

Global Health Crosscutting

Policy Analysis

R&D Capacity Strengthening

Regulatory

US

World Health Organization Consultative Expert Working Group on Research and Development: Financing and Coordination
Research and Development to Meet Health Needs in Developing Countries: Strengthening Global Financing and Coordination

Landmark report from a special body set up by the World Health Organization (WHO) to examine models to finance health R&D for neglected diseases. Provides recommendations to inform WHO’s work in this area.

PDF

Report

Global Health Crosscutting

Access

Case studies

Funding

Incentives & Innovative Financing

Multilateral

Policy Analysis

Sustaining progress: Creating US policies to spur global health innovation

Third annual policy report outlining actions the US government can take to help reduce deaths, extend lives, and secure healthier futures by supporting research for new global health tools.

Learn More

Fact Sheet

Report

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Policy Analysis

Regulatory

R&D Capacity Strengthening

US

Partnerships that bear fruit

Wendy Taylor, former special advisor for innovative finance and public-private partnerships and former director of the Center for Accelerating Innovation and Impact at the US Agency for International Development, discusses how product development partnerships are starting to bear fruit for global health R&D. This video is part of a series on sustaining research progress.

View

Video

Global Health Crosscutting

Funding

Incentives & Innovative Financing

US

Global health research in Kenya: The impact of R&D in the field

Video showing the breadth of US global health R&D in Kenya, which includes projects supported by US agencies. The United States is currently overseeing and supporting more than 60 scientific studies in Kenya on a range of infectious diseases.

View

Video

Global Health Crosscutting

Case studies

Funding

US

An opportunity to fight neglected diseases

Monique Wasunna, head of the Drugs for Neglected Diseases initiative's Africa office, talks about how the United States has an opportunity to invest in research for neglected tropical diseases such as African sleeping sickness, and visceral leishmaniasis. This video is part of a series on sustaining research progress.

View

Video

NTDs

Funding

US

An exciting time for science

Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases at the US National Institutes of Health, talks about why this is an incredibly exciting time for global health R&D. This video is part of a series on sustaining research progress.

View

Video

Global Health Crosscutting

US

Creating huge impact at low cost

Kemy Monahan, former deputy executive director of the US Global Health Initiative, explains why investing in global health R&D is critical to overall US health and development efforts. This video is part of a series on sustaining research progress.

View

Video

Global Health Crosscutting

US

US Centers for Disease Control and Prevention
CDC Global Health Strategy, 2012–2015

Outlines the strategy guiding the global health activities of the US Centers for Disease Control and Prevention (CDC).

PDF

Government Policy

Global Health Crosscutting

R&D Capacity Strengthening

US

Amie Batson on why Americans should care about global health research

Amie Batson, former deputy assistant administrator for global health at the US Agency for International Development and current chief strategy officer at PATH, explains in this video why Americans should care about global health R&D.

View

Video

Global Health Crosscutting

US

Congressman Ed Markey on why Americans should care about global health research

Former Massachusetts congressman and current senator Ed Markey explains in this video why Americans should care about global health R&D.

View

Video

Global Health Crosscutting

US

FDA Commissioner Margaret Hamburg on why Americans should care about global health research

Former US Food and Drug Administration commissioner Margaret Hamberg explains in this video why Americans should care about global health R&D.

View

Video

Global Health Crosscutting

Regulatory

US

Whoopi Goldberg on why Americans should care about global health research

Actress, political activist, and talk show host Whoopi Goldberg explains in this video why Americans should care about global health R&D.

View

Video

Global Health Crosscutting

US

Kaiser Family Foundation
Innovative Financing Mechanisms for Global Health: Overview & Considerations for US Government Participation

Presents an inventory of innovative financing mechanisms that are currently in use or proposed for global health, examines US participation in these mechanisms, and explores potential policy barriers and opportunities for further US government engagement.

PDF

Report

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Policy Analysis

US

Congressional Research Service
Centers for Disease Control and Prevention Global Health Programs: FY2001–FY2012 Request

Provides analysis of the US Center for Disease Control and Prevention’s (CDC) involvement in global health activities, including an overview of CDC’s global health related programs, priorities, and spending.

PDF

Report

Global Health Crosscutting

Funding

Policy Analysis

R&D Capacity Strengthening

US

Sparking innovation to save lives: How the US can advance global health through new technologies

Second annual GHTC policy report documenting promising policy actions taken over the past year in the areas of US investments in global health and international development, regulatory pathways to ensure the safety and efficacy of health tools, and incentives and innovative financing mechanisms to spur global health product development.

Learn More

Fact Sheet

Report

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Policy Analysis

Regulatory

US

The transformative power of global health research

Examines how US leadership in global health research helps to save lives worldwide and provides domestic economic benefits.

PDF

Fact Sheet

Global Health Crosscutting

Economic Impact

US

Exploring the role of the US government in a future advance market commitment

Provides specific recommendations for US policymakers about the role and engagement of the US government in a future advance market commitment.

PDF

Fact Sheet

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Policy Analysis

US

Results for Development Institute
Prizes for Global Health Technologies

Lays out a framework for assessing the potential use of prize programs to incentivize private-sector involvement in health R&D and offers a detailed analysis of prize program proposals for new diagnostic tests for tuberculosis.

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Report

Global Health Crosscutting

Access

Funding

Incentives & Innovative Financing

Policy Analysis

US

Incentives and innovative financing for global health product development

Explores different incentives and innovative financing mechanisms and their roles in global health product development.

PDF

Fact Sheet

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Policy Analysis

US

Innovation in action: Policies to accelerate the development and delivery of global health tools

First annual GHTC policy report focusing on GHTC's three priority areas—US policies related to public financing, regulatory pathways, and incentives and innovating financing.

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Fact Sheet

Report

Global Health Crosscutting

Funding

Incentives & Innovative Financing

Policy Analysis

R&D Capacity Strengthening

Regulatory

US

Center for Strategic & International Studies
Innovative Financing for Global Health: A Moment for Expanded U.S. Engagement?

Evaluates the promise of innovative financing and incentive mechanisms to mobilize increased funding for global health, including R&D, and explores the potential for further US engagement in this area.

PDF

Report

Global Health Crosscutting

Funding

HIV/AIDS

Policy Analysis

US

Drugs for Neglected Diseases initiative, The George Institute for International Health
Registering new drugs: The African Context

Examines hurdles to safe, rapid registration of drugs for use in African nations and suggests solutions to streamline and strengthen regional and international regulatory policies.

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Report

Global Health Crosscutting

Access

Case studies

Multilateral

Policy Analysis

R&D Capacity Strengthening

Regulatory

US

Institute of Medicine of the National Academies
The US Commitment to Global Health: Recommendations for the public and private sectors

Analyzes the commitment and involvement of the US government and US-based nongovernmental organizations, universities, foundations, and commercial entities in global health, including health R&D. Includes recommendations for policy actions the US government can take to accelerate progress on improving global health.

PDF

Report

Global Health Crosscutting

Access

Funding

Health Impact Data

Incentives & Innovative Financing

Policy Analysis

R&D Capacity Strengthening

US

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