Research and development resources

The following reports, fact sheets, and articles from the global health community provide further insight into global health research and development.

Research and development

Product Development Partnership Infographic

This infographic from Research!America highlights the unique strengths of a Product Development Partnership (PDP) relationship by illustrating two different PDP research and development pipelines.

Author: Research!America

Publication date: October 2011

Georgia and economic impact of global health research and development

This factsheet from Research!America examines the impact that domestic global health research has on the Georgia economy.

Author: Research!America

Publication date: August 2011

Staying the Course? Malaria Research and Development in a Time of Economic Uncertainty (2.74 MB PDF)

This analysis of progress in the global fight against malaria has found a four-fold increase in annual funding for malaria research and development (R&D) in just 16 years—from $121 million in 1993 to $612 million in 2009, with a particularly rapid increase since 2004. The funding has generated the largest-ever pipeline of malaria control and prevention products, including new drugs, vaccines, insecticides, and diagnostics.

Author: Policy Cures

Publication date: June 2011

The U.S. Commitment to Global Health R&D (630 KB PDF)

This factsheet published by Research!America outlines the current US commitment to global health research and development (R&D) for new tools and technologies and shows the impact of US investment in global health R&D.

Author: Research!America

Publication date: February 2011

Making Evidence Work for Communities:The Role of Nongovernmental Organizations in Translating Science to Programs (133 KB PDF)

This article published in the Journal of Women's Health explores the unique position that nongovernmental organizations (NGOs) have in implementing evidence-informed public health solutions and fostering research to develop new appropriate interventions and solutions.

Authors: Jennifer Kidwell Drake, M.P.H., Jane E. Hutchings, M.P.H.,and Christopher J. Elias, M.D., M.P.H.

Publication date: November 11, 2010

Accelerating the development of an AIDS vaccine: A U.S. policy agenda (1.18 MB PDF)

This fact sheet from the International AIDS Vaccine Initiative (IAVI) explores key US policy priorities for AIDS vaccine development. The fact sheet also offers concrete suggestions for policy changes to ensure AIDS vaccine development can continue and flourish.

Author: IAVI

Publication date: November 2010

Why is research essential to stop TB? (1.78 MB PDF)

This fact sheet from the Stop TB Partnership highlights how research plays a critical role in eliminating tuberculosis (TB) worldwide. The fact sheet explores the different types of research and their significant impact on reducing the global disease burden of TB and explains how much funding there currently is for research and development and how much is needed in the future.

Author: Stop TB Partnership

Publication date: November 2010

Innovative Product Development Partnerships (3.82 MB PDF)

This policy brief highlights the characteristics and key accomplishments of product development partnerships (PDPs), nonprofit organizations working to fill gaps in the research and development pipeline for drugs, vaccines, microbicides, and diagnostics against diseases of the developing world. The International AIDS Vaccine Initiative developed this brief in collaboration with the Aeras Global TB Vaccine Foundation, the Drugs for Neglected Diseases Initiative, the Foundation for Innovative Diagnostics, the Global Alliance for TB Drug Development, the International Partnership for Microbicides, the Medicines for Malaria Venture, and PATH.

Author: International AIDS Vaccine Initiative

Publication date: September 2010

Research and the Millennium Development Goals (203.32 KB PDF)

This fact sheet from the Global Health Technologies Coalition examines how research for new global health tools can help achieve the Millennium Development Goals.

Author: Global Health Technologies Coalition

Publication date: September 2010

Leveraging research in foreign assistance (128.9 KB PDF)

This fact sheet from the Global Health Technologies Coalition examines the role of innovation in international development and makes recommendations to elevate global health research in the foreign aid reform process.

Authors: Global Health Technologies Coalition

Publication date: July 2010

Asking the right questions: Advancing an HIV research agenda for women and children (1.42 MB PDF)

This document, a consensus statement from 16 leading public- and private-sector organizations working on HIV/AIDS, provides 20 specific recommendations to improve access to to effective HIV prevention, treatment, and care for women and children.

Authors: International AIDS Society; amFAR; AIDS Vaccine Advocacy Coalition; Boehringer Ingelheim; Clinton Health Access Initiative; Coalition on Children Affected by AIDS; Elizabeth Glaser Pediatric AIDS Foundation; European AIDS Treatment Group; International Community of Women Living with HIV/AIDS; International Treatment Preparedness Coalition; Merck & Co.; Treatment Action Group; UNAIDS; UNICEF; ViiV Healthcare; World Health Organization.

Publication date: March 2010

Beating the brain drain: West African research centre shows it can be done (website)

This June 2009 article on the website TropIKA.net describes the Malaria Research Training Centre’s attempts to attract and retain African scientists studying malaria.

Innovation in action: Policies to accelerate the development and delivery of global health tools (1.56 MB PDF)

The first annual report of the Global Health Technologies Coalition (GHTC) focuses on the GHTC's three priority areas—US policies related to public financing, regulatory pathways, and incentives and innovating financing. It highlights the role US agencies and policymakers play in advancing innovation for global health products, as well as makes policy recommendations to help accelerate the development of new global health technologies.

Authors: Global Health Technologies Coalition

Publication date: April 2010

Investing in vaccines for the developing world (website)

This fact sheet, accessed from the PATH website, details the cost of developing and distributing vaccines and outlines innovative funding solutions designed to address these issues.

Medical research: What’s it worth? Estimating the economic benefits from medical research in the UK (2.0 KB PDF)

This report arises from an effort to compile a quantative assessment of the benefit of medical research to the United Kingdom by comparing the macroeconomic benefits accruing from medical research with the cost of that research. 

Authors: Health Economics Group, Brunel University; Office of Health Economics: RAND Europe

Publication date: November 2008

Neglected disease pipeline (website)

This website from BIO Ventures for Global Health features information on 16 neglected diseases of the developing world. The site gives background information on each disease, including existing tools like vaccines and drugs, the medicines that are still needed, potential markets, and the current product pipeline.

Policies and practices to advance global health technologies: A report of the CSIS Global Health Policy Center (673 KB PDF)

This report presents arguments for supporting research and development in global health technologies and includes policy recommendations to help ensure that the United States remains a leader in the field.

Author: Dr. Christopher J. Elias, Center for Strategic & International Studies

Publication date: April 2009

Spurring Innovation in AIDS Vaccine R&D: What Will it Take? (1,327 KB PDF)

This policy brief from the International AIDS Vaccine Initiative explores a variety of mechanisms seeking to generate solutions to global health problems, including the need for new HIV and AIDS technologies. It includes recommendations on how to move forward in creating an appropriate enabling environment for innovative ideas and approaches.

Author: International AIDS Vaccine Initiative

Publication Date: April 2009

The US commitment to global health: Recommendations for the public and private sectors (2.13 KB PDF)

This book outlines the commitment of the US government, nongovernmental organizations, universities, foundations, and commercial entities to global health, including suggestions for actions to accelerate progress on improving global health.

Authors: Committee on the US Commitment to Global Health; Institute of Medicine of the National Academies

Publication date: 2009