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March 2011

The Institute for OneWorld Health announces milestone in cholera drug development

March 2, 2011 -- The Institute for OneWorld Health (iOWH) recently announced a major milestone in the development of a drug to treat cholera and other infectious diarrheal diseases. The US Food and Drug Administration (FDA) granted iOWH permission to begin Phase I trials for iOWH032, a drug to treat secretory diarrhea. The experimental treatment could be the first synthetic drug of its kind for diarrheal diseases. According to iOWH Chief Executive Officer Richard Chin, the organization aims to begin Phase I trials by April 2011.

“It is hard to overstate the need for this kind of medicine. Diarrheal diseases—such as cholera—kill more children in developing countries than AIDS, tuberculosis, and malaria combined,” Chin said. He added, “Nearly five thousand children die every day because of these diseases. Of all childhood infectious diseases, these have the greatest effect on growth, by reducing appetite, altering feeding patterns, and decreasing absorption of nutrients. The number of episodes in the first two years of life also affects fitness, cognitive function, and school performance.” See the link below for more information.

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