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Global health R&D delivers for South Dakota

US government investment in global health R&D has delivered

$1.2 million
to South Dakota research institutions

Neglected diseases in South Dakota

Chikungunya cases
2
Dengue cases
10
HIV diagnoses
250
Malaria cases
24
Tuberculosis cases
129
West Nile cases
683
Zika cases
3

South Dakota's top USG-funded global health R&D institutions

South Dakota State University
$1.2 million

South Dakota industry in global health R&D

Auratus Bio
Location(s):
Canton
Medgene Labs
Location(s):
Brookings
SAB Biotherapeutics
Location(s):
Sioux Falls

South Dakota's top areas of global health R&D by USG funding

66.6%
Malaria
33.4%
Diarrheal diseases

Global health R&D at work in South Dakota

Researchers at South Dakota State University are part of a consortium of global organizations working to develop a vaccine against enterotoxigenic E. coli, or ETEC, a deadly diarrheal disease. The scientists altered the toxins produced by a form of E. coli and genetically fused this non-poisonous "toxoid" to a protein known to evoke an immune response. The resulting "fusion protein" could be used to develop a vaccine. Besides causing diarrheal illness in farm animals, ETEC is a main source of bacterial-induced diarrhea in low-income countries and is the chief cause of traveler's diarrhea. Unsafe water sources and lack of adequate sanitation increase the risk of contracting ETEC. The World Health Organization estimates that ETEC causes approximately 210 million cases of illness in humans and 380,000 deaths each year, most of whom are young children.

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