From Breakthroughs Blog: 2016

 
PATH/Dunia Faulx
A year in review: The top stories in global health innovation that shaped 2016

As the year comes to an end, GHTC is reflecting on the top stories in global health innovation that made news 2016. 

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David Jacobs
Research Roundup: Virus mapping, Zika complications, and antibiotic development

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Architect of the Capitol
Research Roundup: HIV drug resistance, the 21st Century Cures Act, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Aaron Joel Santos
Research Roundup: A Zika treatment, an HIV cure, and a MERS vaccine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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A cornucopia of thanks

In the spirit of the Thanksgiving holiday, GHTC asked our members and staff to share what they are most thankful for in global health.

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National Institute of Allergy and Infectious Diseases
Research Roundup: Long-lasting pills, HIV testing, and starving bacteria of iron

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Gena Morgan
Why GHTC is joining the call for an essential diagnostics list

An essential diagnostic list list in a smart, cost-effective idea that could advance diagnostic R&D and access.

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National Institute of Allergy and Infectious Diseases
Research Roundup: Treating drug-resistant infections, Ebola virus mutations, and Zika vaccine clinical trials

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Katrina Peach
TB epidemic looms large in era of declining R&D funding

October 2016 delivered two sobering wake-up calls: The tuberculosis (TB) epidemic is larger than many realized, and TB R&D has has fallen to its lowest level in seven years.

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National Institute of Allergy and Infectious Diseases
Research Roundup: Cow antibodies, Zika’s impact on male fertility, and hepatitis C research

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Rob Oxley/DFID
DFID lays out vision to tackle global challenges through investments in research

The United Kingdom’s Department for International Development released it’s first-ever research review, laying out a vision for how it will invest £390 million in research and technology per year over the next four years to tackle the world’s toughest challenges.

PATH
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National Institute of Allergy and Infectious Diseases
Research Roundup: Gene editing, mosquito takeover, and decoys for drug resistance

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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David Jacobs
Research Roundup: Pharmaceutical waste and superbugs, resistance to insecticides, and vaccines for crises

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Army Medicine
Research Roundup: Ebola treatment, black widow virus, and Zika syndrome

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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National Institute of Allergy and Infectious Diseases
Research Roundup: Flu vaccines, HIV in kids, and a cross-continental R&D partnership

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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TB Alliance
Research Roundup: Kid-friendly TB treatment, drug manufacturing on-the-go, diarrheal disease, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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UN Photo/Joao Araujo Pinto
How did global health R&D fare at UNGA 71?

The 71st United Nations General Assembly (UNGA) concluded this week. Breakthroughs gives a synopsis of the key global health R&D issues discussed at the assembly and what actions were taken.

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GHTC/Matthew Robinson
The world commits to the AMR fight

At the United Nations General Assembly, world leaders made an unprecedented collective commitment to fighting the growing problem of antimicrobial resistance. GHTC and Global Health Council analyze what that commitment entails, why it matters, and the importance of what happens next.

Global Health Council
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CDC/James Gathany
Research Roundup: Clinical trial data, Mayaro virus, antimicrobial resistance, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Evelyn Hockstein/PATH
Research Roundup: Trojan horse antibody against Ebola, the breakthrough that led to Hepatitis C cures, and Zika infection in monkeys

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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UN Photo/Loey Felipe
UNGA 2016: The world wakes up to AMR

The midtown Manhattan mayhem begins with the opening of the 71st United Nations General Assembly. GHTC preview the global health policy issues that will be discussed at this year's assembly.

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US Centers for Disease Control and Prevention
New information for innovation: Antimicrobial Resistance Isolate Bank

A new tool from the US Centers for Disease Control and Prevention is helping researchers develop diagnostic tests and antibiotics to combat the growing problem of antibiotic resistance.

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PATH/Robin Biellik
Research Roundup: Diagnostics to combat antimicrobial resistance, vaccines for pandemic threats, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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National Institute of Allergy and Infectious Diseases, National Institutes of Health
Research Roundup: A cancer fighting parasite, drug resistance among STIs and fungi, and a first-of-its-kind virus

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Maurizio De Angelis/ Wellcome Images
Research Roundup: Your brain on Zika

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week. In this edition, we cover new insights into the impact of the Zika virus on the brain.

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David Jacobs
Research Roundup: Antibiotics, Zika vaccine R&D, and Ebola and malaria co-infection

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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GHTC
Farewell from the GHTC Director

Erin Will Morton offers farewell thoughts on her last day as GHTC's director.

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CDC/Sue Partridge, CDC- Ft. Collins
Twenty six current and past ASTMH presidents call for Congress to act on Zika funding

Twenty six current and past presidents of the American Society of Tropical Medicine and Hygiene sent a letter urging Congress to pass an emergency spending bill to combat the Zika virus as soon as possible.

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PATH/Dan Chang
Research Roundup: Rapid test for bacterial infections, one drug to treat three neglected diseases, and innovations to combat Zika

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Courtney Carson/GHTC
From DC to Atlanta: Becoming Better Advocates for CDC Global Health Programs on Capitol Hill

Global health advocates traveled to the US Centers for Disease Control and Prevention last month. Here's what they learned about the agency's work.

Global Health Council
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PATH/Evelyn Hockstein
Progress report on health R&D: A Q&A with USAID

USAID's Neal Brandes answers our questions about the agency's latest Health-Related Research and Development Progress Report and USAID's ongoing support for global health R&D.

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Achim Hoerauf/Uniklinik Bonn
Research Roundup: Promising Zika drugs, micro-QR codes to fight counterfeit drugs, and a new antibiotic R&D accelerator

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Marissa Chmiola/GHTC
The potential, the pitch, and the prize: Innovators compete to save maternal and newborn lives

During the pitches at the Saving Lives at Birth DevelopmentXChange, the questions being asked were not how large the market, but how great the need, and not how much money can be made, but how many lives could be saved.

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National Institute of Allergy and Infectious Diseases, National Institutes of Health
Research Roundup: Placenta-on-a-chip, nasal bacteria against MRSA, and an experimental yellow fever vaccine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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International Partnership for Microbicides
Research Roundup: The HIV/AIDS and STIs edition

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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National Institute of Allergy and Infectious Diseases
Research Roundup: Update on Zika R&D

In this regular feature on Breakthroughs, we highlight the most promising Zika virus vaccine, drug, and diagnostic candidates as well as vector control approaches. 

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James Gathany
Research Roundup: Viral hepatitis, treatment for persistent Ebola, E. coli–based vaccines

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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Sanofi Pasteur / Patrick Boulen
Yellow fever: Status of research, development, and access to countermeasures against an emerging epidemic

GHTC breaks down the status of R&D for vaccines, drugs, and diagnostics against yellow fever.

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PATH, as secretariat of GHTC
Eight keys to success in building an effective coalition

We share our lessons learned in building a diverse, effective advocacy coalition for global health R&D.

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National Institute of Allergy and Infectious Diseases (NIAID)
Research Roundup: TB drug development, mosquitoes’ secret weapon, and a new platform for antibiotic R&D

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Aaron Joel Santos
Celebrating over a decade of global health R&D advocacy

From humble origins to the premier advocacy organization focused on global health R&D. We tell the story of the birth of GHTC.

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Architect of the Capitol
Research Roundup: Priority Review Voucher legislation, Toxic Shock Syndrome vaccine, and repurposing existing drugs

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Gabe Bienczycki
Research Roundup: Schistosomiasis drug resistance, a nanotechnology vaccine platform, and adjusting doses to bolster the yellow fever vaccine supply

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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US Navy
Senate votes to protect medical research at DoD

Today the US Senate voted to protect critical medical research programs at the Department of Defense (DoD).

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Gabe Bienczycki
Research Roundup: Diagnostics for malaria, premature birth, and women’s health

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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GHTC/Matthew Robinson
One week of WHA, extensive debate, and two key R&D decisions

As happens every May, the World Health Organization’s (WHO) highest governing body, the World Health Assembly (WHA), met last week for its 69th annual meeting in Geneva, Switzerland. The agenda was the most packed in recent memory, consisting of more than 70 discussion items, many of which were controversial. Despite the lengthy agenda and difficult conversations, the WHA made two key decisions impacting global health research and development (R&D).

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PATH
Research Roundup: Antimicrobial R&D, pandemic insurance, and Zika countermeasures

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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David Dorward / National Institute of Allergy and Infectious Diseases
Research Roundup: antimicrobial resistance, microbiomes, and more

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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WHO
WHO's doing WHA for the 69th time next week!

This coming week the “who’s who” of the global health community (as well as some much more modest global health advocates such as your humble author) will make the annual trek to Geneva, Switzerland, for the 69th World Health Assembly (WHA), where World Health Organization (WHO) member states will collectively decide WHO’s plans for the coming year.

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PATH/Glenn Austin
Research Roundup: New insights into Zika virus, using silk to preserve blood samples, and a single dose oral cholera vaccine

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Jan Jacobs
Research Roundup: a rapid diagnostic for Ebola and fighting mosquito-borne diseases with soap and coconuts

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Doune Porter
Research Roundup: Yellow fever vaccine availability, protective antibodies against HIV, and the impact of past dengue infection on Zika fever

In this regular feature on Breakthroughs, we highlight some of the most interesting reads in global health research from the past week.

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PATH/Lesley Reed
Incentives and innovative financing mechanisms matter in addressing market failures

When existing market forces alone fall short in ensuring availability of and access to lifesaving health tools, a range of interventions are needed to alter the market and ultimately change the behavior of its actors.

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GHTC/Marissa Chmiola
GHTC briefing highlights critical role of US government in advancing global health innovation in an increasingly globalized world

On Tuesday, GHTC launched our seventh annual policy report through a congressional briefing and panel discussion. The critical role played by the US government in catalyzing global health research and development was a recurring theme, as panelists discussed the interconnectedness of global and American health and emphasized the need for new health tools to protect against outbreaks and continue progress.

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PATH/A. Golden
Research Roundup: an affordable hepatitis C regimen, rapid diagnostics for neglected diseases, and fighting Zika with tires and milk

GHTC member the Drugs for Neglected Diseases initiative will test an affordable hepatitis C regimen in Malaysia and Thailand, with a guarantee from generic drug manufacturer Pharco Pharmaceuticals that, if successful, the product will be priced at no more than US$294 for the entire regimen.

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Research Roundup: legislation to expedite antibiotic R&D, a graduated approach to drug patents, and more

Scientists have described the first “teenage” broadly neutralizing antibody—an early stage version of the molecule, before developing the traits that make it effective against manifold HIV strains.

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Funding by crisis is no cure for global health threats

The Zika virus outbreak reinforces the need for US policymakers to stop funding by crisis and commit to sustainable, long-term investment in global health R&D.

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President will redirect Ebola funds for Zika, but where is the money from and where will it go?

The Administration announced that it will transfer nearly $600 million in remaining Ebola funds to fight the growing threat of Zika virus. But many questions remain. Where is the money going? What accounts is it coming from? And what does this mean for the Global Health Security Agenda?

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Research Roundup: Mosquitos and mice in the fight against Zika

Is it feasible or wise to eradicate mosquitoes? Could genetically-modified mosquitoes help researcher tackle the Zika virus? Learn more in this week's Research Roundup.

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Research Roundup: Identifying people at-risk for TB, a device to aid IUD insertion, and vaccines against cancer

In this week's Research Roundup, we look at gene risk for tuberculosis, a new tool to help with inserting IUDs, and vaccines to prevent and treat cancer.

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Take 1.5 minutes for 1.5 million lives

In this guest post, Dara Erck, vice president of External Affairs at Aeras, a global nonprofit biotechnology organization, highlights a new video launched on World TB Day to raise awareness of the urgent need for new tools to combat tuberculosis (TB).

Aeras
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Research Roundup: cash prizes for R&D, genetically modified mosquitoes, and drones for rapid diagnosis

US Senator Bernie Sanders (I-VT) released a plan last week as part of his Democratic presidential bid to incentivize research and development (R&D) for new HIV/AIDS medicines while ensuring they remain affordable.

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Research Roundup: antibiotic resistance in preemies, a low-cost TB test, and more

A new study out of the Washington University School of Medicine in St. Louis, Missouri, revealed a proliferation of antibiotic-resistant bacteria in the gastrointestinal tracts of premature infants.

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Innovative health tools put the power of protection in women’s hands

This International Women’s Day, GHTC is celebrating two novel, female-initiated health technologies that have the potential to give women and girls greater control over their sexual and reproductive health, empowering them to make informed decisions about whether and when to have children and to protect themselves and their families from HIV and other sexually transmitted infections (STIs).

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Research Roundup: A novel single-pill HIV treatment, a promising Ebola therapy, and a collaboration between Google and UNICEF to map Zika

Gilead Sciences, a California-based biopharmaceutical company, has received US Food and Drug Administration (FDA) approval for Odefsey®, a complete, single-pill regimen for HIV/AIDS.

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Better together? Five takeaways on the proposal for a WHO pooled fund

Last week, GHTC convened a panel of experts to dissect and discuss a proposal for pooled funding for global health research and development (R&D).

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Research Roundup: A vaginal ring to prevent HIV, antibodies against Ebola, and the US response to malaria

GHTC member the International Partnership for Microbicides (IPM) announced last week the results of two phase 3 clinical trials demonstrating that a monthly vaginal ring filled with the antiretroviral drug dapivirine can reduce the risk of HIV infection in women.

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Research Roundup: Vaccines for Rift Valley Fever, MERS, and Zika

A vaccine candidate against Rift Valley Fever appears to be safe and effective for livestock and has the potential for use in humans.

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A vaccine is essential to conclusively end HIV/AIDS: New modeling data catalyzes conversations around the end of HIV/AIDS and a vaccine’s role in getting there

In this guest post Tom Harmon, senior policy analyst at the International AIDS Vaccine Initiative (IAVI), highlights a new analysis exploring the critical role of a vaccine in ending AIDS.

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WHO says “no thanks” to the private sector

There’s an old adage about political negotiating: “You need to be in the room when things are happening if you want to have an impact.”

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Research Roundup: Thermal blankets for preemies, remote critical care, and mechanisms to accelerate Zika R&D

Many of the 15 million babies born premature each year struggle with hypothermia and need help to stay warm.

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Ebola funding boost hides ongoing decline in neglected disease R&D

In this guest post, Anna Doubell, an analyst at Policy Cures, writes about the findings of this year’s G-FINDER report on neglected disease research and development (R&D). Supporting data from the report was released this week and is now available online through the G-FINDER public search tool.

Policy Cures
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CDC/Dr. Scott Smith
Global health R&D in the President’s FY17 budget request

On Monday, President Obama released his proposed budget for fiscal year 2017 (FY17).

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Research Roundup: Drones to bolster supply chains, a mobile vaccine manufacturing kit, expanding access to new insecticides, and Zika vaccines

To bypass unreliable roads, a project funded by the Bill & Melinda Gates Foundation and the United Nations Population Fund is using drones to deliver contraceptives, condoms, and other health supplies to remote villages in sub-Saharan Africa.

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WHO Board addresses health R&D, sets March meeting to discuss CEWG resolution

Over 1,000 attendees, a longer than ever agenda—with time management by a song for punishment and a chocolate Caramello Koala as a reward—the 138th World Health Organization (WHO) Executive Board (EB), chaired with humor and efficiency by Precious Matsoso, Director-General of the Department of Health, South Africa, concluded Saturday, January 30 after six days of discussion and debate.

GHTC
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New affordable oral cholera vaccine receives WHO prequalification

In January, GHTC member International Vaccine Institute (IVI) announced that a new oral cholera vaccine it developed in partnership with Korean biotech company EuBiologics, Co. Ltd.—Euvichol®—received prequalification from the World Health Organization (WHO), paving the way for the vaccine to be purchased by global procurement bodies like Gavi, the Vaccine Alliance and UNICEF.

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Research Roundup: Zika edition

The US National Institutes of Health (NIH) is ramping up research for a vaccine against Zika, a mosquito-borne virus which is “spreading explosively” throughout the Americas and can cause birth defects, including microcephaly, which is associated with stunted head and brain development in newborns.

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Setting the stage: UN High-Level Panel on Access to Medicines to consider IP, trade, human rights, and access to medicine

In November 2015, United Nations (UN) Secretary-General Ban Ki-moon convened a High-Level Panel on Access to Medicines to discuss and develop solutions to promote innovation and access to essential medicines, vaccines, diagnostics, and other health technologies needed to ensure health and well-being around the world.

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Major R&D gaps exist for eight pathogens most likely to cause next epidemic

Last month, the World Health Organization (WHO) convened experts to determine which emerging diseases could become “the next Ebola”—those pathogens most likely to cause the next major epidemic.

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Research Roundup: an Ebola vaccine, stillbirths, and antimicrobial R&D

Gavi, the Vaccine Alliance, signed an advanced purchase commitment, pledging to spend US$5 million on an Ebola vaccine currently under development by pharmaceutical company Merck & Co.

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WHO’s Doing What?

With the New Year underway, GHTC is looking forward to a busy spring of multilateral organization meetings—with a number of them impacting global health research and development (R&D). First on the agenda is the World Health Organization (WHO) Executive Board (EB) meeting on January 25–30 in Geneva, where the EB will receive updates on a number of topics and make important decisions, particularly around how to proceed with the next steps of the Consultative Expert Working Group on Research and Development: Financing and Coordination (CEWG) process.

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Research Roundup: Vaccines for cholera and river blindness and an online platform for pooled procurement

Last week, an oral cholera vaccine received World Health Organization (WHO) prequalification, a process of regulatory review which paves the way for procurement by United Nations agencies and international organizations.

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Harnessing health innovation to achieve the global goals

On January 1, the countdown to 2030 officially began with the implementation of the new global development goals.

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Welcoming the National Action Plan for Combating Multidrug-Resistant Tuberculosis: Important first steps, critical next steps

In this guest post, Dara Erck, vice president of external affairs at Aeras, discusses the new White House National Action Plan for Combating Multidrug-Resistant Tuberculosis and how it could accelerate research and development (R&D) of new technologies to combat multidrug-resistant TB (MDR-TB).

Aeras
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Obama highlights global health and innovation in State of the Union

GHTC has long championed US leadership in global health and innovation, and we were encouraged to see President Barack Obama highlight these themes in his State of the Union address.

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Research Roundup: Ebola treatments, drug-resistant gonorrhea, and zoonotic tuberculosis

A recent clinical trial found that convalescent plasma therapy, a treatment in which the blood plasma is taken from survivors of a disease and used to treat current patients, did not prove to be effective against Ebola.

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